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A TNF superfamily member (TNFSF14, 240 aa), a type II transmembrane protein produced by activated T cells that forms a membrane-anchored homotrimeric complex. Herpes simplex virus (HSV) envelope glycoprotein D binds to this complex and the virus gets internalized. A sensible abbreviation for homologous to lymphotoxins, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes’.

Subjects: Medicine and Health.

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