Overview

ERBIN


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A protein (ErbB2 receptor-interacting protein, 1412 aa) of the LAP (leucine-rich repeat (LRR) and PDZ domain) family that binds to p0071 and ErbB2 and colocalizes with PAPIN on the lateral membrane of epithelial cells. Appears to play a regulatory role in the activation by epidermal growth factor of the Ras–Raf–MEK pathway.

Subjects: Medicine and Health.


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