Retrovirus first found in the woolly monkey (q.v.). This oncogenic virus carries the v-sis oncogene, which encodes a transforming protein p28sis. Nucleotide sequences related to v-sis have been located on human chromosome 22 at a site subsequently called c-sis. See Chronology, 1983, Doolittle et al.; platelet-derived growth factor, proto-oncogene, Rous sarcoma virus.
Subjects: Genetics and Genomics.