Article

The Association Between Measures of Inflammation and Psychological Factors Associated with an Increased Risk of Atherosclerotic Cardiovascular Disease: Hostility, Anger and Depressed Mood and Symptoms

Edward C. Suarez

in The Oxford Handbook of Psychoneuroimmunology

Published in print July 2012 | ISBN: 9780195394399
Published online November 2012 | | DOI: http://dx.doi.org/10.1093/oxfordhb/9780195394399.013.0010

Series: Oxford Library of Psychology

 The Association Between Measures of Inflammation and Psychological Factors Associated with an Increased Risk of Atherosclerotic Cardiovascular Disease: Hostility, Anger and Depressed Mood and Symptoms

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Inflammation is acknowledged as a risk factor for the onset and development of cardiovascular disease (CVD). This has led some to hypothesize that inflammation is a possible mechanism that may mediate, in part, the relation of CVD to factors associated with increased CVD risk—hostility, anger, and depression. This chapter reviews the empirical evidence of the associations between biomarkers of inflammation and hostility, anger and depression, alone and in combination. Before doing so, I present a brief description and review of the role of inflammation in disease development and the methods used to measure inflammation at point-of-care and in research laboratories. Lastly, I review preliminary data suggesting that gender and adiposity may potentially mediate and moderate the relationship between depression and inflammation.

Keywords: Inflammation; cytokines; hostility; anger; depression; depressive symptoms; cardiovascular disease; gender

Article.  18893 words. 

Subjects: Psychology ; Health Psychology ; Social Psychology

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