Tms in Migraine

Jean Schoenen, Valentin Bohotin and Alain Maertens De Noordhout

in Oxford Handbook of Transcranial Stimulation

Published in print January 2008 | ISBN: 9780198568926
Published online November 2012 | | DOI:

Series: Oxford Library of Psychology

 Tms in Migraine

More Like This

Show all results sharing these subjects:

  • Psychology
  • Neuropsychology
  • Cognitive Neuroscience


Show Summary Details


Transcranial magnetic stimulation (TMS) has been used to search for cortical dysfunction in migraine. Both, the motor and the visual cortices have been explored in this area. This article reviews and discusses the results of the various studies performed in migraine patients with TMS of motor or visual cortices. The majority of evoked and event-related potential studies in migraine have shown two abnormalities: increased amplitude of grand averaged responses and lack of habituation in successive blocks of averaged responses with decreased amplitude in the first block. These abnormalities suggest that the excitability state of the cerebral cortex, particularly of the visual cortex, is abnormal in migraineurs between attacks. The use of TMS to assess motor and visual cortex excitability has yielded conflicting results, which could be due to methodological differences. Taken together, all studies indicate that the changes in cortical reactivity are more complex in migraineurs than initially thought and suggest that both larger multidisciplinary studies and focused analyses of subgroups of patients with more refined clinical phenotypes are necessary to disentangle the role of the cerebral cortex in migraine pathophysiology.

Keywords: cortical dysfunction; motor and visual cortices; cerebral cortex; migraine patients; migraine pathophysiology

Article.  5702 words. 

Subjects: Psychology ; Neuropsychology ; Cognitive Neuroscience

Full text: subscription required

How to subscribe Recommend to my Librarian

Buy this work at Oxford University Press »

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.