Article

Hair bundle structure and mechanotransduction

Carole M. Hackney and David N. Furness

in Oxford Handbook of Auditory Science: The Ear

Published in print January 2010 | ISBN: 9780199233397
Published online November 2012 | | DOI: http://dx.doi.org/10.1093/oxfordhb/9780199233397.013.0008

Series: Oxford Library of Psychology

Hair bundle structure and mechanotransduction

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  • Cognitive Neuroscience
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This article focuses on the structure, function, and composition of the transduction apparatus of mammalian cochlear hair cells. Hair cells are the sensory receptors of the vertebrate acousticolateralis system. There are two types of hair cell, a single row of inner hair cells (IHCs), and three rows of outer hair cells (OHCs). Hair cell mechanotransduction must result from the fastest known ion channel kinetics. The range of frequencies that can be detected is based on a number of structural modifications along the length of the cochlea including the size and shape of the stereociliary bundles as well as functional variation of the mechanoelectric transducer channels themselves. More recent research in human genetics and molecular biology has begun to identify cellular and molecular mechanisms underlying hair cell mechanotransduction.

Keywords: mechanotransduction; transduction; cochlear hair cells; inner hair cells; outer hair cells; stereociliary bundles

Article.  12805 words. 

Subjects: Psychology ; Cognitive Neuroscience ; Cognitive Psychology

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