Article

Bifunctional nanomaterials for the imaging and treatment of cancer

A. Burke, D. Carroll, Frank Torti and S.V. Torti

in Oxford Handbook of Nanoscience and Technology

Published in print February 2010 | ISBN: 9780199533060
Published online July 2017 | e-ISBN: 9780191701085 | DOI: http://dx.doi.org/10.1093/oxfordhb/9780199533060.013.13

Series: Oxford Handbooks

Bifunctional nanomaterials for the imaging and treatment of cancer

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This article examines the potential of bifunctional nanomaterials for the imaging and treatment of cancer. Several nanomaterials possess properties desirable for a cancer therapy and have been the subject of research as anticancer agents. Those that have received the most attention include encapsulated iron oxides, single- and multiwalled carbon nanotubes, gold nanorods and gold nanoshells. This article first considers thermal ablative therapy incancer, focusing on the mechanisms of thermotoxicity and thermoresistance before discussing a number of nanomaterials with applications for cancer treatment. In particular, it evaluates the use of nanomaterials in thermal therapy. It also looks at gold nanoshells and nanorods, taking into account their physical properties, and concludes with an assessment of iron-oxide nanoparticles and future directions for nanomaterials as multifunctional agents for cancer therapy.

Keywords: bifunctional nanomaterials; cancer; nanomaterials; cancer therapy; thermal ablative therapy; cancer treatment; thermal therapy; gold nanoshells; gold nanorods; iron-oxide nanoparticles

Article.  12595 words. 

Subjects: Semiconductor and Mesoscopic Physics

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