Journal Article

Serum myoglobin and creatine kinase following surgery

A. S. Laurence

in BJA: British Journal of Anaesthesia

Published on behalf of the British Journal of Anaesthesia

Volume 84, issue 6, pages 763-766
Published in print June 2000 | ISSN: 0007-0912
Published online June 2000 | e-ISSN: 1471-6771 | DOI:
Serum myoglobin and creatine kinase following surgery

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Serum myoglobin (by radioimmunoassay) and creatine kinase were measured for up to 7 days in 30 patients following surgical procedures, including total hip replacement and bilateral subcostal abdominal incisions. Serum myoglobin reached a maximum of 1390 μg litre–1 (median 345 μg litre–1 for major surgery patients) on the first postoperative day but levels were still elevated by day 7 in some patients. Creatine kinase reached a maximum of 1339 i.u. litre–1 at day 2 (median 422 i.u. litre–1 for major surgery patients), generally peaking 1 day after myoglobin in individual patients. These values may have significance when investigating a suspicion of coincident perioperative events such as myocardial infarction or malignant hyperthermia.

Keywords: muscle, skeletal, myoglobin; surgery

Journal Article.  0 words. 

Subjects: Anaesthetics

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