Journal Article

A Zinc-Finger-Type Transcription Factor WZF-1 That Binds to a Novel <i>cis</i>-Acting Element Element of Histone Gene Promoters Represses Its Own Promoter

Ayako Sakamoto, Serik Omirulleh, Takuya Nakayama and Masaki Iwabuchi

in Plant and Cell Physiology

Published on behalf of Japanese Society of Plant Physiologists

Volume 37, issue 4, pages 557-562
Published in print June 1996 | ISSN: 0032-0781
e-ISSN: 1471-9053 | DOI: http://dx.doi.org/10.1093/oxfordjournals.pcp.a028980
A Zinc-Finger-Type Transcription Factor WZF-1 That Binds to a Novel cis-Acting Element Element of Histone Gene Promoters Represses Its Own Promoter

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WZF-1 is a zinc-finger protein which binds to the wheat histone gene promoter. Southwestern-binding analyses revealed that it bound a CACTC sequence, a novel positive cis-acting element. The activity of WZF-1 gene promoter, containing six CACTC sequences, was markedly reduced when WZF-1 was co-expressed, suggesting that WZF-1 is a transcriptional repressor.

Keywords: ACT-box; Autoregulation; Repressor; Wheat; Zinc-finger-protein

Journal Article.  0 words. 

Subjects: Biochemistry ; Molecular and Cell Biology ; Plant Sciences and Forestry

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