Journal Article

Laterality in Animals: Relevance to Schizophrenia

Patricia E. Cowell, Roslyn Holly Fitch and Victor H. Denenberg

in Schizophrenia Bulletin

Published on behalf of Maryland Psychiatric Research Center

Volume 25, issue 1, pages 41-62
Published in print January 1999 | ISSN: 0586-7614
Published online January 1999 | e-ISSN: 1745-1701 | DOI:
Laterality in Animals: Relevance to Schizophrenia

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Anomalies in the laterality of numerous neurocognitive dimensions associated with schizophrenia have been documented, but their role in the etiology and early development of the disorder remain unclear. In the study of normative neurobehavioral organization, animal models have shed much light on the mechanisms underlying and the factors affecting adult patterns of both functional and structural asymmetry. Nonhuman species have more recently been used to investigate the environmental, genetic, and neuroendocrine factors associated with developmental language disorders in humans. We propose that the animal models used to study the basis of lateralization in normative development and language disorders such as dyslexia could be modified to investigate lateralized phenomena in schizophrenia.

Keywords: Animal models; laterality in animals; functional and structural asymmetry; language; hand preference

Journal Article.  0 words. 

Subjects: Child and Adolescent Psychiatry

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