Journal Article

The challenge to improve the response of biomaterials to the physiological environment

Nicholas A. Peppas and John R. Clegg

in Regenerative Biomaterials

Published on behalf of Chinese Society for Biomaterials

Volume 3, issue 2, pages 67-71
Published in print June 2016 | ISSN: 2056-3418
Published online March 2016 | e-ISSN: 2056-3426 | DOI: http://dx.doi.org/10.1093/rb/rbw012

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  • Reproductive Medicine
  • Biological Engineering
  • Materials Science

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New applications of biomaterials often require advanced structures containing synthetic and natural components that are tuned to provide properties unique to a specific application. We discuss how structural characteristics of biomaterials, especially hydrophilic ones, can be used in conjunction with non-ideal thermodynamics to develop advanced medical systems. We show a number of examples of biocompatible, intelligent biomaterials that can be used for organ replacement, biosensors, precise drug delivery over days or weeks, and regenerative medicine.

Keywords: drug delivery; nanobiomaterials; regenerative mechanism; materials structure

Journal Article.  2489 words.  Illustrated.

Subjects: Reproductive Medicine ; Biological Engineering ; Materials Science

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