Journal Article

The depth-dependence of the biological effectiveness of <sup>60</sup>Co gamma rays in a large absorber determined by dicentric chromosomes in human lymphocytes

Ernst Schmid, Hartmut Roos and Hans-Michael Kramer

in Radiation Protection Dosimetry

Volume 130, issue 4, pages 442-446
Published in print July 2008 | ISSN: 0144-8420
Published online March 2008 | e-ISSN: 1742-3406 | DOI: https://dx.doi.org/10.1093/rpd/ncn069
The depth-dependence of the biological effectiveness of 60Co gamma rays in a large absorber determined by dicentric chromosomes in human lymphocytes

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Radiobiological evidence is shown concerning a significant depth-dependence of the maximum relative biological effectiveness at limiting low doses (RBEM) of 60Co gamma rays in a cubic polymethylmethacrylate (PMMA) phantom of 30 cm edge length. Using the dose–response curve for the dicentric data in human lymphocytes obtained in the present experiment at a depth of 20 cm, together with the comprehensive and consistent data set determined earlier at smaller depths of the PMMA phantom, there is an increase in the RBEM value by a factor of 2.18 ± 1.25 at a depth of 20 cm relative to 1 cm in the phantom. All the dicentric data are based on identical exposure durations and irradiation temperatures as well as identical culture and evaluation conditions, with blood from the same donor.

Journal Article.  3108 words.  Illustrated.

Subjects: Nuclear Chemistry, Photochemistry, and Radiation

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