Journal Article

Mortality Among Patients With Schizophrenia

John C. Simpson and Ming T. Tsuang

in Schizophrenia Bulletin

Published on behalf of Maryland Psychiatric Research Center

Volume 22, issue 3, pages 485-499
Published in print January 1996 | ISSN: 0586-7614
e-ISSN: 1745-1701 | DOI:
Mortality Among Patients With Schizophrenia

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Results from a 40-year followup study of psychotic patients are presented to illustrate some of the major findings and unanswered questions about excess mortality in schizophrenia and to suggest analytical approaches that take full account of the potential effects of sample heterogeneity. In this study, hospital-diagnosed schizophrenia patients were at increased mortality risk whether or not they met research criteria for schizophrenia. In addition, mortality outcomes of several major diagnostic groups were similar despite substantial clinical and demographic differences between the groups at baseline. These results suggest that both diagnosis-specific and nondiagnostic factors are needed to account for excess mortality in patients with major psychiatric disorders. The issue of heterogeneity is also crucial for the clinical purposes of predicting and ultimately reducing the mortality risk of psychiatric patients, for example, in delineating profiles of high-risk patients who are not necessarily typical of other patients with the same diagnosis.

Journal Article.  0 words. 

Subjects: Child and Adolescent Psychiatry

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