Journal Article

Synthesizing Schizophrenia: A Bottom-Up, Symptomatic Approach

Trevor W Robbins

in Schizophrenia Bulletin

Published on behalf of Maryland Psychiatric Research Center

Volume 31, issue 4, pages 854-864
Published in print January 2005 | ISSN: 0586-7614
Published online January 2005 | e-ISSN: 1745-1701 | DOI: http://dx.doi.org/10.1093/schbul/sbi044
Synthesizing Schizophrenia: A Bottom-Up, Symptomatic Approach

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The cognitive deficits in schizophrenia are discussed in terms of the other symptoms of the disorder, as well as according to a translational approach that involves using similar or analogous tests for humans and experimental animals. This approach, it is argued, will enable the testing of novel drugs and the development of adequate etiological models of schizophrenia.

Keywords: cognition; memory; attention; prefrontal cortex; psychosis; dopamine

Journal Article.  8311 words.  Illustrated.

Subjects: Child and Adolescent Psychiatry

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