Journal Article

Catatonia and Its Treatment

Patricia I. Rosebush and Michael F. Mazurek

in Schizophrenia Bulletin

Published on behalf of Maryland Psychiatric Research Center

Volume 36, issue 2, pages 239-242
Published in print March 2010 | ISSN: 0586-7614
Published online December 2009 | e-ISSN: 1745-1701 | DOI:
Catatonia and Its Treatment

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Psychiatric diagnoses are currently categorized on a syndromic basis. The syndrome of catatonia, however, remains in a diagnostic limbo, acknowledged predominantly as a subtype of schizophrenia. Yet, catatonia is present in about 10% of acutely ill psychiatry patients, only a minority of whom have schizophrenia. Among those with comorbid affective disorders, who comprise the largest subgroup of catatonic patients, the catatonic signs typically resolve dramatically and completely with benzodiazepine therapy. Those with schizophrenia respond less reliably, suggesting that the underlying processes causing the catatonia may be different in this group. The majority of patients with catatonia have concurrent psychosis. Failure to treat the catatonia before institution of antipsychotic medication may increase the risk of inducing neuroleptic malignant syndrome. At this point of time, the pathobiology of catatonia is unknown; the major reason for considering catatonia as a separate diagnostic entity would be to increase recognition of this eminently treatable neuropsychiatric syndrome.

Keywords: catatonia; treatment; benzodiazepines

Journal Article.  2543 words. 

Subjects: Child and Adolescent Psychiatry

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