Journal Article

Brief report. Cure of β-thalassaemia major by umbilical cord blood transplantation - a case report of Malaysia's first cord blood transplantation

C Lee-Lee and L Hai-Peng

in Journal of Tropical Pediatrics

Volume 45, issue 4, pages 243-245
Published in print August 1999 | ISSN: 0142-6338
Published online August 1999 | e-ISSN: 1465-3664 | DOI: http://dx.doi.org/10.1093/tropej/45.4.243
Brief report. Cure of β-thalassaemia major by umbilical cord blood transplantation - a case report of Malaysia's first cord blood transplantation

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A 25-month-old boy with β-thalassaemia major was presented with an opportunity for umbilical cord blood transplantation when his unborn sibling was diagnosed in utero to be a β-thalassaemia carrier and also human leucocyte antigen compatible. A barely adequate amount of cord blood was collected at the birth of his sibling and infused into the patient after appropriate chemo-conditioning. Engraftment occurred without major complications. The subject is now alive and well 9 months post-transplant, thus marking our first success in umbilical cord blood transplantation.

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Subjects: Paediatrics ; Antitrust Issues and Policies

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