Journal Article

Brief report. Acute respiratory tract infections in Indian children with special reference to <i>Mycoplasma pneumoniae</i>

A Pandey, R Chaudhry, N Nisar and SK Kabra

in Journal of Tropical Pediatrics

Volume 46, issue 6, pages 371-374
Published in print December 2000 | ISSN: 0142-6338
Published online December 2000 | e-ISSN: 1465-3664 | DOI:
Brief report. Acute respiratory tract infections in Indian children with special reference to Mycoplasma pneumoniae

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A total of 70 Indian children of either sex and under 5 years of age who were admitted to the All India Institute of Medical Sciences, New Delhi during a 1-year period (January 1994-December 1994) with complaints suggestive of acute respiratory tract infections (ARTI), were investigated for bacterial aetiology of infection with special reference to Mycoplasma pneumoniae. Microbial aetiology could be established in 44/70 (62.8 per cent) of cases of ARTI. Mycoplasma pneumoniae infection was seen in 21/70 (30 per cent), aerobic bacteria in 14/70 (20 per cent), Chlamydia pneumoniae in 2/70 (2.8 per cent), and mixed infection with mycoplasma either with bacteria and/or chlamydia in 7/70 (10 per cent). However, in 26/70 (37.1 per cent) cases no cause could be detected. Diagnosis of infection with M.pneumoniae was based on culture in 2/20 (10 per cent) cases, antigen detection in throat swab by indirect immunofluorescence assay using specific antibody in 16/70 (22.8 per cent) cases, and demonstration of IgM antibody in serum by serodia Myco II particle agglutination test in 17/70 (24.2 per cent). Streptococcus pneumoniae (9/70, 12.8 per cent) and Staphylococcus aureus (5/70, 7.1 per cent) were the aerobic isolates from blood in these patients. Results of this study indicate that M.pneumoniae plays a significant role in respiratory tract infection in an Indian paediatric population. Rapid diagnostic procedures, such as antigen detection and IgM antibody demonstration, should be used more widely to determine the infective aetiology early in the course of illness. The study also highlights the mixed aetiology in ARTI in children, which has important therapeutic implications.

Journal Article.  0 words. 

Subjects: Paediatrics

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