Journal Article

Cerebrospinal Fluid Lysozyme Level for the Diagnosis of Tuberculous Meningitis in Children

O. P. Mishra, P. Batra, Z. Ali, S. Anupurba and B. K. Das

in Journal of Tropical Pediatrics

Volume 49, issue 1, pages 13-16
Published in print February 2003 | ISSN: 0142-6338
Published online February 2003 | e-ISSN: 1465-3664 | DOI: http://dx.doi.org/10.1093/tropej/49.1.13
Cerebrospinal Fluid Lysozyme Level for the Diagnosis of Tuberculous Meningitis in Children

Show Summary Details

Preview

Lysozyme activity was assayed in the cerebrospinal fluid (CSF) of 32 tuberculous meningitis (TBM), 17 bacterial meningitis, 10 partially treated bacterial meningitis, 18 encephalitis and 18 control subjects. The mean CSF lysozyme activity was significantly raised (p < 0.001) in TBM patients compared with other study groups. A cut‐off CSF lysozyme level of ≥ 26 U/l had a sensitivity and specificity of 93.7 and 84.1 per cent, respectively for the diagnosis of TBM. Overall, it was found to be a better test than any other single test and thus can be used for rapid and early diagnosis of TBM in children.

Journal Article.  0 words. 

Subjects: Paediatrics

Full text: subscription required

How to subscribe Recommend to my Librarian

Users without a subscription are not able to see the full content. Please, subscribe or login to access all content.