Journal Article

Carnitine Levels in Neonatal Hypoxia

Halıt Çam, Behçet Yildirim, Ahmet Aydin and Aysu Say

in Journal of Tropical Pediatrics

Volume 51, issue 2, pages 106-108
Published in print April 2005 | ISSN: 0142-6338
Published online April 2005 | e-ISSN: 1465-3664 | DOI: http://dx.doi.org/10.1093/tropej/fmh089
Carnitine Levels in Neonatal Hypoxia

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Background: The aim of this study is to determine carnitine levels in hypoxic–ischemiac neonates.

Methods: Total and free carnitine levels were measured in 20 normal term neonates and 20 term neonates who were diagnosed as hypoxia–ischemia.

Results: Both total carnitine levels (43.7 ± 10.0 μg/dl vice 27.8 ± 11.8 μg/dl, p<0.0001) and free carnitine levels (28.0 ± 8.8 vice 13.2 ± 6.8 μg/dl, p<0.0001) were lower in the hypoxic–ischemic group). Additionally acyl/total carnitine ratio was higher in the asphyxic group (0.33 ± 0.20 vice 0.56 ± 0.24, p<0.0001).

Conclusions: The findings of this study show that neonates with hypoxia–ischemia suffer carnitine deficiency.

Journal Article.  0 words. 

Subjects: Paediatrics

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