Journal Article

Residual Goiter in Semirom; Iodine Status and Thiocyanate Overload Do Not Play a Role

Ammar Hassanzadeh Keshteli, Mahin Hashemipour, Masoud Amini, Mansour Siavash, Ashraf Aminorroaya, Hassan Rezvanian, Ali Kachuei and Roya Kelishadi

in Journal of Tropical Pediatrics

Volume 56, issue 3, pages 216-217
Published in print June 2010 | ISSN: 0142-6338
Published online October 2009 | e-ISSN: 1465-3664 | DOI: http://dx.doi.org/10.1093/tropej/fmp096
Residual Goiter in Semirom; Iodine Status and Thiocyanate Overload Do Not Play a Role

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This study was performed to investigate the role of thiocyanate overload in the etiology of endemic goiter in schoolchildren of Semirom, Iran. A total of 1828 schoolchildren were selected by multi-stage random sampling. Urinary iodine concentration (UIC) and urinary thiocyanate (USCN) were measured in a group of these children. The median UIC was 18.5 µg/dl. The mean ± SD of USCN in goitrous and nongoitrous subjects did not differ significantly (0.75 ± 0.78 mg/dl vs. 0.63 ± 0.40 mg/dl; p = 0.30). Finally, we concluded that neither iodine deficiency nor thiocyanate overload contributed to the high prevalence of goiter in Semirom. The role of other goitrogenic factors should be investigated in this region.

Keywords: goiter; iodine deficiency; goitrogens; thiocyanate; Iran

Journal Article.  661 words. 

Subjects: Paediatrics

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