Journal Article

Milk-based Cornstarch Porridge Fortified with Iron is Effective in Reducing Anemia: A Randomized, Double-blind, Placebo-controlled Trial

Francisco Plácido Nogueira Arcanjo, Cecília Costa Arcanjo, Francisco Carlos Nogueira Arcanjo, Lício de Albuquerque Campos, Olga Maria Silverio Amancio and Josefina Aparecida Pellegrini Braga

in Journal of Tropical Pediatrics

Volume 58, issue 5, pages 370-374
Published in print October 2012 | ISSN: 0142-6338
Published online February 2012 | e-ISSN: 1465-3664 | DOI: http://dx.doi.org/10.1093/tropej/fms003
Milk-based Cornstarch Porridge Fortified with Iron is Effective in Reducing Anemia: A Randomized, Double-blind, Placebo-controlled Trial

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This study evaluates the impact of a milk-based cornstarch porridge fortified with iron, in 4-year olds, compared with control on hemoglobin levels and anemia prevalence. This trial was a cluster-randomized, double-blind one, and used milk-based cornstarch porridge fortified with 10 mg elemental iron (FeSO4), daily, during 14 weeks, compared with control. The study population comprised 4-year-old preschoolers (n = 131). Mean hemoglobin values at baseline were found to be 10.6 ± 0.61 g dl−1 for intervention group, and after intervention 11.5 ± 0.80 g/dl, p < 0.0001. For control, mean hemoglobin values at baseline were 10.9 ± 0.53 g/dl, and after intervention 11.2 ± 0.73, p < 0.0001. The increase in mean hemoglobin was much greater in the intervention than in the control group, 0.86–0.26 g dl−1, respectively (p < 0.0001). Anemia prevalence reduced from 75% to 20%, p < 0.0001, in the intervention group, with no reduction in the control group. Number needed for treatment was four. This study showed that milk-based cornstarch porridge fortified with ferrous sulfate increased hemoglobin levels and reduced anemia prevalence in 4-year-old preschoolers.

Keywords: iron; anemia; preschoolers; cornstarch; hemoglobins; iron fortification

Journal Article.  2423 words.  Illustrated.

Subjects: Paediatrics

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