Journal Article

Cloning of an <i>agr</i> homologue of <i>Staphylococcus saprophyticus</i>

Türkan Sakinc, Pawel Kulczak, Karsten Henne and Sören G Gatermann

in FEMS Microbiology Letters

Volume 237, issue 1, pages 157-161
Published in print August 2004 |
Published online January 2006 | e-ISSN: 1574-6968 | DOI: http://dx.doi.org/10.1111/j.1574-6968.2004.tb09691.x

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An agr homologue of Staphylococcus saprophyticus was identified, cloned and sequenced. The gene locus shows homologies to other staphylococcal agr systems, especially to those of S. epidermidis and S. lugdunensis. A putative RNAIII was identified and found to be differentially expressed during the growth phases. In contrast to the RNAIII molecules of S. epidermidis and S. aureus it does not contain an open reading frame that codes for a protein with homologies to the d-toxin. Using PCR, the agr was found to be present in clinical isolates of S. saprophyticus.

Keywords: Staphylococcus saprophyticus; agr; Gene regulation

Journal Article.  2713 words.  Illustrated.

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