Journal Article

Relationship between biofilm formation, the enterococcal surface protein (Esp) and gelatinase in clinical isolates of <i>Enterococcus faecalis</i> and <i>Enterococcus faecium</i>

Roberta Di Rosa, Roberta Creti, Mario Venditti, Raffaele D'Amelio, Carla R. Arciola, Lucio Montanaro and Lucilla Baldassarri

in FEMS Microbiology Letters

Volume 256, issue 1, pages 145-150
Published in print March 2006 |
Published online February 2006 | e-ISSN: 1574-6968 | DOI:

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One-hundred and twenty-eight enterococcal isolates were examined for their ability to form biofilm in relation to the presence of the gene encoding the enterococcal surface protein (esp), production of gelatinase and to the source of isolation. Neither esp nor gelatinase seemed to be required for biofilm formation: both Enterococcus faecalis and Enterococcus faecium did not show a correlation between the presence of either esp or the production of gelatinase and biofilm formation. However, in E. faecium while esp was found in isolates from either source, the presence of both esp and biofilm together was only found in strains from clinical settings, suggesting that there exists a synergy between these factors which serves as an advantage for the process of infection.

Keywords: enterococci; biofilm; esp; gelatinase; virulence

Journal Article.  3401 words.  Illustrated.

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