Journal Article

Inducible hydroxylation and demethylation of the herbicide isoproturon by <i>Cunninghamella elegans</i>

Martin Hangler, Bo Jensen, Stig Rønhede and Sebastian R. Sørensen

in FEMS Microbiology Letters

Volume 268, issue 2, pages 254-260
Published in print March 2007 |
Published online February 2007 | e-ISSN: 1574-6968 | DOI:

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A screening of 27 fungal strains for degradation of the phenylurea herbicide isoproturon was performed and yielded 15 strains capable of converting the herbicide to polar metabolites. The zygomycete fungus Cunninghamella elegans strain JS/2 isolated from an agricultural soil converted isoproturon to several known hydroxylated metabolites. In addition, unknown metabolites were produced in minor amounts. Inducible degradation was indicated by comparing resting cells pregrown with or without isoproturon. This shows that strain JS/2 is capable of partially degrading isoproturon and that one or more of the enzymes involved are inducible upon isoproturon exposure.

Keywords: pesticide bioconversion; physiological response; fungi

Journal Article.  3417 words.  Illustrated.

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