Chapter

Strategies for Efficient Exploitation of the Informational Content of Protein Multiple Alignments

Anne Friedrich, Olivier Poch and Luc Moulinier

in Sequence Alignment

Published by University of California Press

Published in print November 2009 | ISBN: 9780520256972
Published online March 2012 | e-ISBN: 9780520943742 | DOI: http://dx.doi.org/10.1525/california/9780520256972.003.0011
Strategies for Efficient Exploitation of the Informational Content of Protein Multiple Alignments

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This chapter focuses on the multiple sequence alignment (MSA) of complete proteins. It first provides an overview of the central role of multiple sequence alignments and their use in a wide range of biological applications, particularly in protein analysis, and then discusses the problem of efficient MSA construction, depending on the biological question being studied. Finally, the chapter considers how the standard applications can be integrated for wider exploitation.

Keywords: multiple sequence alignment; MSA; proteins; protein analysis; MSA construction

Chapter.  7903 words.  Illustrated.

Subjects: Evolutionary Biology

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