Chapter

Pharmaceutical Knowledge-Capital Accumulation and Longevity

Frank R. Lichtenberg

in Measuring Capital in the New Economy

Published by University of Chicago Press

Published in print October 2005 | ISBN: 9780226116129
Published online February 2013 | e-ISBN: 9780226116174 | DOI: http://dx.doi.org/10.7208/chicago/9780226116174.003.0008
Pharmaceutical Knowledge-Capital Accumulation and Longevity

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This chapter evaluates the contribution of pharmaceutical research and development (R&D) to longevity increase by analyzing the relationship between Food and Drug Administration (FDA) approvals of new molecular entities and changes in the age distribution of deaths from all diseases, using longitudinal disease-level data. It explains the measurement of pharmaceutical knowledge-capital accumulation and proposes an econometric model of the effect of pharmaceutical knowledge-capital accumulation on the age distribution of deaths. The findings reveal that the estimates indicated that approval of standard-review drugs has no effect on longevity, but that approval of priority-review drugs has a significant positive impact on longevity.

Keywords: pharmaceutical R&D; longevity increase; FDA; new molecular entities; age distribution; knowledge-capital accumulation; econometric model; priority-review drugs; longevity

Chapter.  13774 words.  Illustrated.

Subjects: Econometrics and Mathematical Economics

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