Journal Article

Antibody detection tests for Onchocerca volvulus: comparison of the sensitivity of a cocktail of recombinant antigens used in the indirect enzyme-linked immunosorbent assay with a rapid-format antibody card test

Mario A. Rodríguez-Pérez, Alfredo Domínguez-Vázque, Jorge Méndez-Galván, Ana M. Sifuentes-Rincón, Patricia Larralde-Coronal, Hugo A. Barrera-Saldaña and Janette E. Bradley

in Transactions of The Royal Society of Tropical Medicine and Hygiene

Published on behalf of Royal Society of Tropical Medicine and Hygiene

Volume 97, issue 5, pages 539-541
Published in print October 2003 | ISSN: 0035-9203
Published online October 2003 | e-ISSN: 1878-3503 | DOI: https://dx.doi.org/10.1016/S0035-9203(03)80018-4
Antibody detection tests for Onchocerca volvulus: comparison of the sensitivity of a cocktail of recombinant antigens used in the indirect enzyme-linked immunosorbent assay with a rapid-format antibody card test

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There is a need for a specific, sensitive, and practical diagnostic test to monitor onchocerciasiselimination campaigns. In April 2001, an enzyme-linked immunosorbent assay (ELISA) using 3 recombinant antigens and a rapid-format antibody card test (immunochromatographic test; ICT) using an individual antigen were compared in a Mexican population with onchocerciasis. The sensitivity of the ELISA and ICT was 97% and 86%, respectively.

Keywords: onchocerciasis; Onchocerca volvulus; diagnosis; detection; immunochromatographic test; enzyme-linkedimmunosorbent assay; Mexico

Journal Article.  0 words. 

Subjects: Clinical Medicine ; Infectious Diseases ; Immunology ; Medical Microbiology and Virology ; Public Health and Epidemiology

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