Journal Article

Additional case of Ramichloridium mackenziei cerebral phaeohyphomycosis from the Middle East

Z. U. Khan, S. J. Lamdhade, M. Johny, J. Al-Khalidi, A. Thussu, H. N. Yossef, I. Al-Obaid and A. A. Nasser

in Medical Mycology

Published on behalf of International Society for Human and Animal Mycology

Volume 40, issue 4, pages 429-433
Published in print January 2002 | ISSN: 1369-3786
Published online January 2002 | e-ISSN: 1460-2709 | DOI: https://dx.doi.org/10.1080/mmy.40.4.429.433
Additional case of Ramichloridium mackenziei cerebral phaeohyphomycosis from the Middle East

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  • Mycology and Fungi
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In this report we describe a case of cerebral phaeohyphomycosis involving a 56-year-old Egyptian male who worked as a mason in Kuwait for 6 years. Computerized tomography scan of the brain revealed presence of a large abscess in the left occipital lobe. Aspirated pus from the abscess showed branched, septate, hyphae with light brown pigmentation. Cultured pus grew the fungus Ramichloridium mackenziei. Despite amphotericin B (1 mg kg−1 per day) therapy for 2 weeks, the patient expired. The isolate was later found to be resistant to amphotericin B (>gt;32 µg ml−1). Antifungal susceptibility testing to other agents was also performed.

Keywords: cerebral phaeohyphomycosis; Kuwait; Middle East; Ramichloridium Mackenziei

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Subjects: Mycology and Fungi ; Infectious Diseases ; Medical Toxicology ; Veterinary Medicine ; Environmental Science

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