Journal Article

The activity of RTA2, a downstream effector of the calcineurin pathway, is required during tunicamycin-induced ER stress response in Candida albicans

Edwina Thomas, Shabnam Sircaik, Elvira Roman, Jean-Michel Brunel, Atul K. Johri, Jesús Pla and Sneh L. Panwar

Edited by Richard Calderone

in FEMS Yeast Research

Published on behalf of Federation of European Microbiological Societies

Volume 15, issue 8 Published in print December 2015 | ISSN: 1567-1356
Published online October 2015 | e-ISSN: 1567-1364 | DOI: https://dx.doi.org/10.1093/femsyr/fov095

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Graphical Abstract Figure.

The downstream effector molecule, RTA2, of the calcineurin pathway regulates Hac1p-dependent expression of genes involved in the unfolded protein response pathway, during tunicamycin-induced ER stress in Candida albicans.

Keywords: Candida albicans; RTA2; unfolded protein response; ER stress; calcineurin; Hac1

Journal Article.  8431 words.  Illustrated.

Subjects: Biotechnology ; Genetics and Genomics ; Microbiology ; Molecular and Cell Biology ; Mycology and Fungi

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