Journal Article

Als1 and Als3 regulate the intracellular uptake of copper ions when Candida albicans biofilms are exposed to metallic copper surfaces

Sha Zheng, Wenqiang Chang, Chen Li and Hongxiang Lou

Edited by Richard Calderone

in FEMS Yeast Research

Published on behalf of Federation of European Microbiological Societies

Volume 16, issue 3 Published in print May 2016 | ISSN: 1567-1356
Published online April 2016 | e-ISSN: 1567-1364 | DOI: https://dx.doi.org/10.1093/femsyr/fow029

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Graphical Abstract Figure.

The cells within Candida albicans biofilms were killed by copper surface contact through influx of copper ions. This effect was inhibited by ALS1 and ALS3 via suppressing the CRP1 expressions.

Keywords: copper surfaces; Candida albicans; biofilms; reactive oxygen species; CRP1

Journal Article.  5020 words.  Illustrated.

Subjects: Biotechnology ; Genetics and Genomics ; Microbiology ; Molecular and Cell Biology ; Mycology and Fungi

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