Journal Article

Examining Clinical Trial Results with Single-Subject Analysis: An Example Involving Behavioral and Nutrition Treatment for Young Children with Cystic Fibrosis

Scott W. Powers, Carrie Piazza-Waggoner, Julie S. Jones, Kathleen S. Ferguson, Cori Daines and James D. Acton

in Journal of Pediatric Psychology

Volume 31, issue 6, pages 574-581
Published in print July 2006 | ISSN: 0146-8693
Published online July 2005 | e-ISSN: 1465-735X | DOI: https://dx.doi.org/10.1093/jpepsy/jsj049
Examining Clinical Trial Results with Single-Subject Analysis: An Example Involving Behavioral and Nutrition Treatment for Young Children with Cystic Fibrosis

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  • Child and Adolescent Psychiatry
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Objective To examine the process of change in a clinical trial of behavioral and nutrition treatment for children age 18–48 months with cystic fibrosis (CF) using single-subject analysis. Methods The 5-week treatment included nutrition counseling and child behavioral management training for parents and was designed to increase energy intake measured by diet diaries 600–800 calories per day. Results Energy intake changed at each meal, only when treatment was introduced (week 1: snacks, 420 to 691; week 2: breakfast, 325 to 443; week 4: lunch, 350 to 443; and week 5: dinner, 373 to 460 calories per day). Total daily intake increased in a systematic fashion that exceeded the criterion set each week during treatment. Conclusions Toddlers and preschoolers with CF meet energy intake recommendations as a result of behavioral intervention. Single-subject research designs are important methodologies for advancing clinical investigation in pediatric psychology.

Keywords: changing criterion design; multiple baseline design; parenting; pediatrics; single case experimental designs

Journal Article.  4179 words.  Illustrated.

Subjects: Child and Adolescent Psychiatry ; Psychology

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