Journal Article

Vernalization-mediated chromatin changes

Brett R. Zografos and Sibum Sung

in Journal of Experimental Botany

Published on behalf of Society for Experimental Biology

Volume 63, issue 12, pages 4343-4348
Published in print July 2012 | ISSN: 0022-0957
Published online June 2012 | e-ISSN: 1460-2431 | DOI:
Vernalization-mediated chromatin changes

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Proper flowering time is vital for reproductive fitness in flowering plants. In Arabidopsis, vernalization is mediated primarily through the repression of a MADS box transcription factor, FLOWERING LOCUS C (FLC). The induction of a plant homeodomain-containing protein, VERNALIZATION INSENSITIVE 3 (VIN3), by vernalizing cold is required for proper repression of FLC. One of a myriad of changes that occurs after VIN3 is induced is the establishment of FLC chromatin at a mitotically repressed state due to the enrichment of repressive histone modifications. VIN3 induction by cold is the earliest known event during the vernalization response and includes changes in histone modifications at its chromatin. Here, the current understanding of the vernalization-mediated chromatin changes in Arabidopsis is discussed, with a focus on the roles of shared chromatin-modifying machineries in regulating VIN3 and FLC gene family expression during the course of vernalization.

Keywords: Chromatin, cold response, epigenetic, flowering, LHP1, PRC2, vernalization

Journal Article.  4813 words.  Illustrated.

Subjects: Plant Sciences and Forestry

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