An fMRI-Based Neurologic Signature of Physical Pain

Edited by Anita Gupta, Elena N. Gutman and Michael E. Hochman

in 50 Studies Every Anesthesiologist Should Know

Published on behalf of Oxford University Press

Published in print December 2018 | ISBN: 9780190237691
Published online January 2019 | e-ISBN: 9780190237721 | DOI:

Series: Fifty Studies Every Doctor Should Know

An fMRI-Based Neurologic Signature of Physical Pain

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This case focuses on fMRI-based neurologic signatures of physical pain by asking the question: Can functional magnetic resonance imaging (fMRI) be used to identify sensitive and specific brain measures of experimental thermal pain in healthy volunteers? This fMRI study identified an interpretable and reproducible neurologic signature of cutaneous pain elicited by noxious heat in healthy volunteers. The interpretation of fMRI neurologic signatures could be useful in situations in which patients are unable to communicate the perception of pain effectively. Further studies are needed to assess whether this signature predicts clinical pain.

Chapter.  905 words.  Illustrated.

Subjects: Anaesthetics

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