Chapter

Psychological morbidity in amyotrophic lateral sclerosis: Depression, anxiety, hopelessness

Dorothée Lulé, Albert C. Ludolph and Andrea Kübler

in Amyotrophic Lateral Sclerosis

Published on behalf of Oxford University Press

Published in print February 2018 | ISBN: 9780198757726
Published online February 2018 | e-ISBN: 9780191817618 | DOI: https://dx.doi.org/10.1093/med/9780198757726.003.0003
Psychological morbidity in amyotrophic lateral sclerosis: Depression, anxiety, hopelessness

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Amyotrophic lateral sclerosis is a devastating condition with progressive loss of movement, speech, and respiratory function, and no available cure. Following the development of clinical symptoms and after receiving a diagnosis, patients may develop psychological morbidity, such as depression, anxiety, and hopelessness. However, many patients adjust successfully in the course of the disease and maintain good psychological well-being, so that a decline in psychological well-being does not necessarily accompany loss of physical function. There are several major determinants of good psychological adjustment to chronic and terminal disease—intrinsic factors such as coping strategies and internal locus of control, and extrinsic factors such as high (perceived and actual) social support by families and multidisciplinary professional teams. Providing care with a holistic view of the patient is probably the most effective approach to supporting patients’ psychosocial adjustment to the disease and minimizing depression, anxiety, and hopelessness.

Chapter.  7597 words.  Illustrated.

Subjects: Neurology ; Development of the Nervous System

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