Chapter

Managing blood lipids

Edited by Catriona Jennings, Ian Graham and Stephan Gielen

in The ESC Handbook of Preventive Cardiology

Published on behalf of Oxford University Press

Published in print June 2016 | ISBN: 9780199674039
Published online July 2016 | e-ISBN: 9780191781865 | DOI: https://dx.doi.org/10.1093/med/9780199674039.003.0014

Series: The European Society of Cardiology Textbooks

Managing blood lipids

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Hypercholesterolaemia, particularly raised low-density lipoprotein cholesterol, relates to cardiovascular disease in a graded manner and the relationship is causal. There is unequivocal evidence that treatment of hyperlipidaemia reduces cardiovascular disease events. European Guidelines retain a targeted approach—the higher the risk, the more intense the therapeutic advice. Current American guidance is for high-dose statin therapy for all very high-risk subjects. High triglycerides and low high-density lipoprotein cholesterol signal increase risk but trials do not support target values. High triglycerides are associated with central obesity, hypertension, low high-density lipoprotein cholesterol, and raised blood sugar. They may respond to weight control and alcohol reduction. Statins may increase blood sugar levels but the benefit associated with low-density lipoprotein lowering outweighs the adverse effect of this.

Chapter.  2426 words.  Illustrated.

Subjects: Cardiovascular Medicine

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