Journal Article

A 19-year-old at 37 weeks gestation with an acute acetylsalicylic acid overdose

Huma Farid, Monica H. Wojcik and Kenneth B. Christopher

in Clinical Kidney Journal

Published on behalf of European Renal Association - European Dialysis and Transplant Assoc

Volume 4, issue 6, pages 394-396
Published in print December 2011 | ISSN: 1753-0784
Published online September 2011 | e-ISSN: 1753-0792 | DOI:

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Acute salicylate overdose in pregnancy is potentially fatal for both the mother and fetus and presents a unique challenge in intensive care management. While suggested thresholds exist for hemodialysis in adults with toxic salicylate ingestion, it is unclear if these thresholds remain appropriate for the gravid patient, particularly given that medications such as acetylsalicylic acid may cross the placental barrier and accumulate in the fetal bloodstream. We describe a case of a gravid patient at ∼37 weeks gestational age with a self-reported acetylsalicylic acid ingestion of 32.5 g and review prior cases of both acute and chronic salicylate ingestion in pregnancy in order to determine the clinical precedent for hemodialysis in this situation.

Keywords: acetylsalicylic acid; hemodialysis; overdose; pregnancy; salicylate toxicity

Journal Article.  1726 words.  Illustrated.

Subjects: Nephrology

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