EC 22.214.171.124; other name: proteinase II; a metalloendopeptidase that catalyses the cleavage of Phe1‐|‐Val2, His5‐|‐Leu6, His10‐|‐Leu11, Ala14‐|‐Leu15, Leu15‐|‐Tyr16, and Tyr16‐|‐Leu17 in the insulin B‐chain. Zn2+ and Ca2+ are cofactors. It ...
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