Journal Article

Activated dormant Cryptococcus gattii infection in a Dutch tourist who visited Vancouver Island (Canada): a molecular epidemiological approach

Ferry Hagen, Sander van Assen, Gert Jan Luijckx, Teun Boekhout and Greetje A. Kampinga

in Medical Mycology

Published on behalf of International Society for Human and Animal Mycology

Volume 48, issue 3, pages 528-531
Published in print May 2010 | ISSN: 1369-3786
Published online May 2010 | e-ISSN: 1460-2709 | DOI: https://dx.doi.org/10.3109/13693780903300319
Activated dormant Cryptococcus gattii infection in a Dutch tourist who visited Vancouver Island (Canada): a molecular epidemiological approach

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  • Mycology and Fungi
  • Infectious Diseases
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An ongoing outbreak of Cryptococcus gattii caused infections, which emerged on Vancouver Island and the Pacific Northwest, has affected more than 200 of the islands' residents, of whom eight died. While C. gattii infections are rarely described in travelers, we report a case of cryptococcosis caused by C. gattii in a patient treated with high dose corticosteroids for systemic lupus erythematosus induced autoimmune hemolytic anemia. She acquired the disease during a visit to Vancouver Island one year before the onset of the symptoms. This indicates that C. gattii may cause a dormant infection that can be activated during treatment with corticosteroids.

Keywords: Cryptococcus gattii; cryptococcosis; latent infection; travel; molecular epidemiology

Journal Article.  2027 words. 

Subjects: Mycology and Fungi ; Infectious Diseases ; Medical Toxicology ; Veterinary Medicine ; Environmental Science

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