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Biochemistry x Science and Mathematics x Neuroendocrinology and Autonomic Nervous System x clear all

Human Dopamine β-Hydroxylase Promoter Variant Alters Transcription in Chromaffin Cells, Enzyme Secretion, and Blood Pressure

Yuqing Chen, Kuixing Zhang, Gen Wen, Fangwen Rao, Amber P. Sanchez, Lei Wang, Juan L. Rodriguez-Flores, Manjula Mahata, Sushil K. Mahata, Jill Waalen, Michael G. Ziegler, Bruce A. Hamilton and Daniel T. O'Connor.

in American Journal of Hypertension

January 2011; p ublished online January 2011 .

Journal Article. Subjects: Neuroendocrinology and Autonomic Nervous System; Biochemistry; Endocrinology and Diabetes. 4715 words.

Background

Dopamine β-hydroxylase (DBH) plays an indispensable role in catecholamine synthesis by converting dopamine into norepinephrine. Here, we...

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Inflammation and Hypertension: The Interplay of Interleukin-6, Dietary Sodium, and the Renin–Angiotensin System in Humans

Bindu Chamarthi, Gordon H. Williams, Vincent Ricchiuti, Nadarajah Srikumar, Paul N. Hopkins, James M. Luther, Xavier Jeunemaitre and Abraham Thomas.

in American Journal of Hypertension

October 2011; p ublished online October 2011 .

Journal Article. Subjects: Neuroendocrinology and Autonomic Nervous System; Biochemistry; Endocrinology and Diabetes. 4420 words.

Background

Prior evidence suggests a link between inflammation and hypertension. Interleukin-6 (IL-6) has been implicated in animal studies to play an...

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Interplay Between miR-155, AT1R A1166C Polymorphism, and AT1R Expression in Young Untreated Hypertensives

Giulio Ceolotto, Italia Papparella, Alessia Bortoluzzi, Giacomo Strapazzon, Fabio Ragazzo, Paolo Bratti, Aline S.C. Fabricio, Elisa Squarcina, Massimo Gion, Paolo Palatini and Andrea Semplicini.

in American Journal of Hypertension

February 2011; p ublished online February 2011 .

Journal Article. Subjects: Neuroendocrinology and Autonomic Nervous System; Biochemistry; Endocrinology and Diabetes. 4206 words.

Background

A silent polymorphism (+1166 A/C single-nucleotide polymorphism) localized in the 3′-UTR (untranslated region) of the human angiotensin II type-1...

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Intraprocedural Cortisol Measurement Increases Adrenal Vein Sampling Success Rate in Primary Aldosteronism

Ermanno Rossi, Giuseppe Regolisti, Franco Perazzoli, Aurelio Negro, Chiara Grasselli, Rosaria Santi, Simonetta Cavalieri, Lucia Belloni, Giuseppe Gemelli, Edoardo Della Valle and Diego Miotto.

in American Journal of Hypertension

December 2011; p ublished online December 2011 .

Journal Article. Subjects: Neuroendocrinology and Autonomic Nervous System; Biochemistry; Endocrinology and Diabetes. 4203 words.

Background

Adrenal venous sampling (AVS) is the gold standard for the identification of unilateral primary aldosteronism (PA), but is technically difficult....

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Metabolic Syndrome Induces Over Expression of the Human AT1R: A Haplotype-Dependent Effect With Implications on Cardio-Renal Function

Sudhir Jain, Nitin Puri, Anita Rana, Natalie Sirianni, Brahmaraju Mopidevi and Ashok Kumar.

in American Journal of Hypertension

March 2018; p ublished online October 2017 .

Journal Article. Subjects: Biochemistry; Neuroendocrinology and Autonomic Nervous System; Endocrinology and Diabetes. 5325 words.

Abstract

BACKGROUND

The transcriptional regulation of the human angiotensin receptor subtype 1 (AT1R) gene in...

Methionine-Induced Homocysteinemia Impairs Endothelial Function in Hypertensives: The Role of Asymmetrical Dimethylarginine and Antioxidant Vitamins

Dimitris Tousoulis, George Bouras, Charalambos Antoniades, Kyriakoula Marinou, Nikolaos Papageorgiou, Antigoni Miliou, George Hatzis, Elli Stefanadi, Costas Tsioufis and Christodoulos Stefanadis.

in American Journal of Hypertension

August 2011; p ublished online August 2011 .

Journal Article. Subjects: Neuroendocrinology and Autonomic Nervous System; Biochemistry; Endocrinology and Diabetes. 4375 words.

Background

Nitric oxide synthase (NOS) inhibitor asymmetrical dimethylarginine (ADMA) is synthesized by the methylation of arginine as part of the...

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Mineralocorticoid Receptor and Cardiovascular Disease

Mathieu Buonafine, Benjamin Bonnard and Frédéric Jaisser.

in American Journal of Hypertension

October 2018; p ublished online September 2018 .

Journal Article. Subjects: Biochemistry; Neuroendocrinology and Autonomic Nervous System; Endocrinology and Diabetes. 9465 words.

Abstract

Activation of the mineralocorticoid receptor (MR) in the distal nephron by its ligand, aldosterone, plays an important role in sodium reabsorption and...

Modulating Role of Ang1-7 in Control of Blood Pressure and Renal Function in AngII-infused Hypertensive Rats

Marta Kuczeriszka, Elżbieta Kompanowska-Jezierska, Janusz Sadowski, Minolfa C Prieto and L Gabriel Navar.

in American Journal of Hypertension

March 2018; p ublished online October 2017 .

Journal Article. Subjects: Anatomy; Nephrology; Biochemistry; Neuroendocrinology and Autonomic Nervous System; Endocrinology and Diabetes. 4873 words.

Abstract

BACKGROUND

Indirect evidence suggests that angiotensin 1-7 (Ang1-7) may counterbalance prohypertensive...

Neuronal Nitric Oxide Synthase Supports Renin Release During Sodium Restriction Through Inhibition of Phosphodiesterase 3

Johan Sällström, Boye L. Jensen, Ole Skøtt, Xiang Gao and A. Erik G. Persson.

in American Journal of Hypertension

November 2010; p ublished online November 2010 .

Journal Article. Subjects: Neuroendocrinology and Autonomic Nervous System; Biochemistry; Endocrinology and Diabetes. 4038 words.

Background

Mice with targeted deletion of neuronal nitric oxide (NO) synthase (nNOS−/−) display inability to increase plasma renin concentration (PRC) in...

Go to »  abstract

Noncoding RNAs in Cardiovascular Disease: Pathological Relevance and Emerging Role as Biomarkers and Therapeutics

Roopesh S Gangwar, Sanjay Rajagopalan, Rama Natarajan and Jeffrey A Deiuliis.

in American Journal of Hypertension

January 2018; p ublished online November 2017 .

Journal Article. Subjects: Endocrinology and Diabetes; Biochemistry; Neuroendocrinology and Autonomic Nervous System. 9483 words.

Abstract

Noncoding RNAs (ncRNA) include a diverse range of functional RNA species—microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) being most studied in...