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Adherence to Dietary Guidelines and Successful Aging Over 10 Years

Bamini Gopinath, Joanna Russell, Annette Kifley, Victoria M. Flood and Paul Mitchell.

in The Journals of Gerontology: Series A

March 2016; p ublished online October 2015 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 4928 words.

Background.

We aimed to prospectively examine the relationship between overall diet quality (reflecting adherence to dietary guidelines) and successful...

Adipogenic Differentiation Is Impaired in Replicative Senescent Human Subcutaneous Adipose-Derived Stromal/Progenitor Cells

Maria C. Mitterberger, Stefan Lechner, Monika Mattesich and Werner Zwerschke.

in The Journals of Gerontology: Series A

January 2014; p ublished online May 2013 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 6891 words.

We demonstrate that adipose-derived stromal/progenitor cells isolated from abdominal subcutaneous fat pads of adult donors successively enter replicative senescence after long-term...

Adipokine Profile and Insulin Sensitivity in Formerly Obese Women Subjected to Bariatric Surgery or Diet-Induced Long-term Caloric Restriction

Maria C. Mitterberger, Monika Mattesich, Elise Klaver, Stefan Lechner, Timm Engelhardt, Lorenz Larcher, Gerhard Pierer, Hildegunde Piza-Katzer and Werner Zwerschke.

in The Journals of Gerontology: Series A

September 2010; p ublished online June 2010 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 5577 words.

To better understand the contribution of the fat mass to the effects of long-term caloric restriction in humans, we compared adipokine profile and insulin sensitivity in long-term...

Adipose Tissue Density, a Novel Biomarker Predicting Mortality Risk in Older Adults

Rachel A. Murphy, Thomas C. Register, Carol A. Shively, J. Jeffrey Carr, Yaorong Ge, Marta E. Heilbrun, Steven R. Cummings, Annemarie Koster, Michael C. Nevitt, Suzanne Satterfield, Frances A. Tylvasky, Elsa S. Strotmeyer, Anne B. Newman, Eleanor M. Simonsick, Ann Scherzinger, Bret H. Goodpaster, Lenore J. Launer, Gudny Eiriksdottir, Sigurdur Sigurdsson, Gunnar Sigurdsson, Vilmundur Gudnason, Thomas F. Lang, Stephen B. Kritchevsky and Tamara B. Harris.

in The Journals of Gerontology: Series A

January 2014; p ublished online May 2013 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 6322 words.

Background.

Knowledge of adipose composition in relation to mortality may help delineate inconsistent relationships between obesity and mortality in old...

Adipose Tissue Infiltration in Skeletal Muscle of Healthy Elderly Men: Relationships With Body Composition, Insulin Resistance, and Inflammation at the Systemic and Tissue Level

Elena Zoico, Andrea Rossi, Vincenzo Di Francesco, Anna Sepe, Debora Olioso, Francesca Pizzini, Francesco Fantin, Ottavio Bosello, Luciano Cominacini, Tamara B. Harris and Mauro Zamboni.

in The Journals of Gerontology: Series A

March 2010; p ublished online October 2009 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 2680 words.

Background

Association between inflammatory markers and intermuscular adipose tissue (IMAT) has been reported. We hypothesized that subclinical inflammation...

Adiposity, Telomere Length, and Telomere Attrition in Midlife: the 1946 British Birth Cohort

Wahyu Wulaningsih, Diana Kuh, Andrew Wong and Rebecca Hardy.

in The Journals of Gerontology: Series A

June 2018; p ublished online August 2017 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 4824 words.

Abstract

Background

Obesity has been linked with shorter telomere length, both of which have been implicated in...

Adopting the ICF Language for Studying Late-life Disability: A Field of Dreams?

Vicki A. Freedman.

in The Journals of Gerontology: Series A

November 2009; p ublished online July 2009 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 1460 words.

Adult Lifetime Diet Quality and Physical Performance in Older Age: Findings From a British Birth Cohort

Sian M Robinson, Leo D Westbury, Rachel Cooper, Diana Kuh, Kate Ward, Holly E Syddall, Avan A Sayer and Cyrus Cooper.

in The Journals of Gerontology: Series A

October 2018; p ublished online October 2017 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 5395 words.

Abstract

Background

Current evidence that links “healthier” dietary patterns to better measured physical...

Advanced Age, Cardiovascular Risk Burden, and Timed Up and Go Test Performance in Parkinson Disease

Vikas Kotagal, Roger L. Albin, Martijn L. T. M. Müller, Robert A. Koeppe, Stephanie Studenski, Kirk A. Frey and Nicolaas I. Bohnen.

in The Journals of Gerontology: Series A

December 2014; p ublished online May 2014 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 5414 words.

Background.

Cardiovascular comorbidities are a known risk factor for impaired mobility in elderly individuals. Motor impairments in Parkinson disease are...

Advanced Glycation End Products Are Associated With Physical Activity and Physical Functioning in the Older Population

Hans Drenth, Sytse U Zuidema, Wim P Krijnen, Ivan Bautmans, Andries J Smit, Cees van der Schans and Hans Hobbelen.

in The Journals of Gerontology: Series A

October 2018; p ublished online April 2018 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 5927 words.

Abstract

Background

Decline in physical activity and functioning is commonly observed in the older population and...

Advanced Glycation End-Products as Markers of Aging and Longevity in the Long-Lived Ansell’s Mole-Rat (Fukomys anselli)

Philip Dammann, David R. Sell, Sabine Begall, Christopher Strauch and Vincent M. Monnier.

in The Journals of Gerontology: Series A

June 2012; p ublished online December 2011 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 6569 words.

Mole-rat of the genus Fukomys are mammals whose life span is strongly influenced by reproductive status with breeders far outliving nonbreeders. This raises the important question of...

Advances in Geroscience: Impact on Healthspan and Chronic Disease

John B. Burch, Alison Deckhut Augustine, Leslie A. Frieden, Evan Hadley, T. Kevin Howcroft, Ron Johnson, Partap S. Khalsa, Ronald A. Kohanski, Xiao Ling Li, Francesca Macchiarini, George Niederehe, Young S. Oh, Aaron C. Pawlyk, Henry Rodriguez, Julia H. Rowland, Grace L. Shen, Felipe Sierra and Bradley C. Wise.

in The Journals of Gerontology: Series A

June 2014; p ublished online May 2014 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 846 words.

Population aging is unprecedented, without parallel in human history, and the 21st century will witness even more rapid aging than did the century just past. Improvements in public health...

Advancing Age Alters the Contribution of Calcium Release From Smooth Endoplasmic Reticulum Stores in Superior Cervical Ganglion Cells

Erik J. Behringer, Conwin K. Vanterpool, William J. Pearce, Sean M. Wilson and John N. Buchholz.

in The Journals of Gerontology: Series A

January 2009; p ublished online February 2009 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 7218 words.

In superior cervical ganglion (SCG) neurons calcium-induced calcium release (CICR), mediated by ryanodine receptors (RyRs), contributes to stimulation-evoked intracellular calcium ([Ca2+]null...

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Adverse Clinical Events and Mortality During Hospitalization and 3 Months After Discharge in Cognitively Impaired Elderly Patients

Alessandra Marengoni, Alessandro Nobili, Valentina Romano, Mauro Tettamanti, Luca Pasina, Sylvestre Djade, Salvatore Corrao, Francesco Salerno, Alfonso Iorio, Maura Marcucci and Pier Mannuccio Mannucci.

in The Journals of Gerontology: Series A

April 2013; p ublished online September 2012 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 5053 words.

Background.

Controversial findings are reported on hospital outcome in cognitively impaired patients. The aim of this study was to explore mortality risk...

Adverse Effects of Diabetes Mellitus on the Skeleton of Aging Mice

Sergio Portal-Núñez, Juan Antonio Ardura, Daniel Lozano, Oskarina Hernández Bolívar, Ana López-Herradón, Irene Gutiérrez-Rojas, Alexander Proctor, Bram van der Eerden, Marijke Schreuders-Koedam, Johannes van Leeuwen, María José Alcaraz, Francisca Mulero, Mónica de la Fuente and Pedro Esbrit.

in The Journals of Gerontology: Series A

March 2016; p ublished online September 2015 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 6858 words.

In the present study, the possibility that a diabetic (DM) status might worsen age-related bone deterioration was explored in mice. Male CD-1 mice aged 2 (young control group) or 16 months,...

Adverse Geriatric Outcomes Secondary to Polypharmacy in a Mouse Model: The Influence of Aging

Aniko Huizer-Pajkos, Alice E. Kane, Susan E. Howlett, John Mach, Sarah J. Mitchell, Rafael de Cabo, David G. Le Couteur and Sarah N. Hilmer.

in The Journals of Gerontology: Series A

May 2016; p ublished online May 2015 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 5640 words.

We aimed to develop a mouse model of polypharmacy, primarily to establish whether short-term exposure to polypharmacy causes adverse geriatric outcomes. We also investigated whether old age...

Aerobic Exercise Plus Weight Loss Improves Insulin Sensitivity and Increases Skeletal Muscle Glycogen Synthase Activity in Older Men

Alice S. Ryan, Leslie I. Katzel, Steven J. Prior, John C. McLenithan, Andrew P. Goldberg and Heidi K. Ortmeyer.

in The Journals of Gerontology: Series A

July 2014; p ublished online December 2013 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 5361 words.

The purpose of this study was to determine the effects of 6-month aerobic exercise training + weight loss (AEX + WL) on basal and insulin activation of glycogen synthase, basal citrate...

Aerobic Exercise Recovers Disuse-induced Atrophy Through the Stimulus of the LRP130/PGC-1α Complex in Aged Rats

Ivan J. Vechetti-Junior, Raquel S. Bertaglia, Geysson J. Fernandez, Tassiana G. de Paula, Rodrigo W. A. de Souza, Leonardo N. Moraes, Edson A. Mareco, Carlos E. A. de Freitas, Andreo F. Aguiar, Robson F. Carvalho and Maeli Dal-Pai-Silva.

in The Journals of Gerontology: Series A

May 2016; p ublished online May 2015 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 6186 words.

Physical training has been shown to be important to the control of muscle mass during aging, through the activation of several pathways including, IGF1-AKT and PGC-1α. Also, it was...

Age- and Menopause-Related Bone Loss Compromise Cortical and Trabecular Microstructure

Ego Seeman.

in The Journals of Gerontology: Series A

October 2013; p ublished online July 2013 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 3863 words.

All factors influencing the material composition and structure of bone do so through the final common cellular pathways of modeling and remodeling. During growth, modeling, the formation of...

Age- and Sex-Associated Plasma Proteomic Changes in Growth Hormone Receptor Gene–Disrupted Mice

Juan Ding, Darlene E. Berryman, Adam Jara and John J. Kopchick.

in The Journals of Gerontology: Series A

August 2012; p ublished online December 2011 .

Journal Article. Subjects: Geriatric Medicine; Public Health; Biological Sciences; Molecular and Cell Biology; Neuroscience. 7798 words.

Growth hormone receptor gene–disrupted (GHR−/−) mice are dwarf, insulin sensitive, and long lived despite being obese. In order to identify characteristics associated with their increased...