A 10S galectin-3–U1 snRNP complex assembles into active spliceosomes
in Nucleic Acids Research
July 2016; p ublished online April 2016 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4810 words.
In previous studies, we reported that fractionation of HeLa cell nuclear extracts on glycerol gradients revealed an endogenous ∼10S particle that contained galectin-3 and U1 snRNP and this...
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A 16S rRNA–tRNA product containing a nucleotide phototrimer and specific for tRNA in the P/E hybrid state in the Escherichia coli ribosome
in Nucleic Acids Research
January 2004; p ublished online January 2004 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6644 words.
Ribosome complexes containing deacyl-[math] or biotinylvalyl-[math] and an mRNA analog have been irradiated with wavelengths specific for activation of the cmo5U nucleoside at position 34 in...
A 1.8 kb Alternative Transcript from the Human Epidermal Growth Factor Receptor Gene Encodes a Truncated form of the Receptor
in Nucleic Acids Research
October 1996; p ublished online October 1996 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4492 words.
The epidermal growth factor receptor (EGFR) is encoded by the c-erbB1 proto-oncogene and plays an important role in the control of cell growth and differentiation. To study the potential...
A 21‐amino acid peptide from the cysteine cluster II of the family D DNA polymerase from Pyrococcus horikoshii stimulates its nuclease activity which is Mre11‐like and prefers manganese ion as the cofactor
in Nucleic Acids Research
January 2004; p ublished online January 2004 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 7265 words.
Family D DNA polymerase (PolD) is a new type of DNA polymerase possessing polymerization and 3′–5′ exonuclease activities. Here we report the characterization of the nuclease activity of...
A 2,2′-bipyridine ligand for incorporation into oligodeoxynucleotides: Synthesis, stability and fluorescence properties of ruthenium—DNA complexes
in Nucleic Acids Research
January 1999; p ublished online January 1999 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4768 words.
A non-nucleoside linker based upon the ligand 2,2′-bipyridine and ethylene glycol is prepared and placed into the backbone of a number of oligonucleo-tides. The bipyridine ligand is reacted...
A 39 Amino Acid Fragment of the Cell Cycle Regulator p21 Is Sufficient to Bind PCNA and Partially Inhibit DNA Replication in vivo
in Nucleic Acids Research
May 1996; p ublished online May 1996 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 4650 words.
The cell cycle regulator p21 interacts with and inhibits the DNA replication and repair factor proliferating cell nuclear antigen (PCNA). We have defined a 39 amino acid fragment of p21...
A 43 kDa DNA Binding Protein from the Pea Chloroplast Interacts with and Stimulates the Cognate DNA Polymerase
in Nucleic Acids Research
October 1996; p ublished online October 1996 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 6663 words.
A DNA binding protein with DNA polymerase ‘accessory activity’ has been identified and purified to apparent homogeneity from pea chloroplasts. This protein consists of a single subunit of...
A 5′, 8-cyclo-2′-deoxypurine lesion induces trinucleotide repeat deletion via a unique lesion bypass by DNA polymerase β
in Nucleic Acids Research
December 2014; p ublished online November 2014 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 9132 words.
5′,8-cyclo-2′-deoxypurines (cdPus) are common forms of oxidized DNA lesions resulting from endogenous and environmental oxidative stress such as ionizing radiation. The lesions can only be...
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A 5′ Untranslated Region Which Directs Accurate and Robust Translation By Prokaryotic and Mammalian Ribosomes
in Nucleic Acids Research
March 1996; p ublished online March 1996 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 1236 words.
A 7-methylguanosine cap commits U3 and U8 small nuclear RNAs to the nucleolar localization pathway
in Nucleic Acids Research
February 1998; p ublished online February 1998 .
Journal Article. Subjects: Chemistry; Biochemistry; Bioinformatics and Computational Biology; Genetics and Genomics; Molecular and Cell Biology. 2699 words.
U3 and U8 small nucleolar RNAs (snRNAs) participate in pre-rRNA processing. Like the U1, U2, U4 and U5 major spliceosomal snRNAs, U3 and U8 RNAs are transcribed by RNA polymerase II and...