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Molecular and Cell Biology x Preclinical Medicine x clear all

3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM

Eugene Y.D. Chua, Vinod K. Vogirala, Oviya Inian, Andrew S.W. Wong, Lars Nordenskiöld, Juergen M. Plitzko, Radostin Danev and Sara Sandin.

in Nucleic Acids Research

September 2016; p ublished online August 2016 .

Journal Article. Subjects: Molecular and Cell Biology; Genetics and Genomics; Research Methods in Life Sciences; Proteins; Molecular Biology and Genetics. 3716 words.

The Volta phase plate is a recently developed electron cryo-microscopy (cryo-EM) device that enables contrast enhancement of biological samples. Here we have evaluated the potential of...

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The A1298C Mutation in Methylenetetrahydrofolate Reductase Gene and Its Association With Idiopathic Venous Thrombosis in an Iranian Population

Mohammad Soleyman Soltanpour, Zahra Soheili, Ali Akbar Pourfathollah, Shahram Samiei, Reza Meshkani, Ali Asghar Kiani, Safa Majid, Zahra Ataei and Mahnaz Kavari.

in Laboratory Medicine

April 2011; p ublished online October 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2806 words.

Background:

Venous thrombosis (VT) is an important cause of mortality and morbidity resulting from acquired and inherited factors. The A1298C mutation of the...

ABA Regulates Subcellular Redistribution of OsABI-LIKE2, a Negative Regulator in ABA Signaling, to Control Root Architecture and Drought Resistance in Oryza sativa

Chengxiang Li, Hongyun Shen, Tao Wang and Xuelu Wang.

in Plant and Cell Physiology

December 2015; p ublished online October 2015 .

Journal Article. Subjects: Molecular Biology and Genetics; Biotechnology; Biochemistry; Bioinformatics and Computational Biology; Molecular and Cell Biology; Plant Sciences and Forestry; Plant Physiology. 8295 words.

The phytohormone ABA is a key stress signal in plants. Although the identification of ABA receptors led to significant progress in understanding the Arabidopsis ABA signaling pathway, there...

ABCA1 and ABCG1 Expression in the Small Intestine of Type 2 Diabetic Rats

Juanya Lou, Huali Zhou, Chengjiang Li, Lingling Hu, Xunliang Lu, Jun Li, Hongtian Yao, Wenpeng Li, Xinxin Zhang and Mingzhi Xu.

in Laboratory Medicine

February 2014; p ublished online September 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 3625 words.

Objective

Inflammation of the small intestine may occur in type 2 diabetes. This study aimed to investigate whether ATP-binding cassette transporter A1...

Abscisic Acid Participates in the Control of Cell Cycle Initiation Through Heme Homeostasis in the Unicellular Red Alga Cyanidioschyzon merolae

Yuki Kobayashi, Hiroyuki Ando, Mitsumasa Hanaoka and Kan Tanaka.

in Plant and Cell Physiology

May 2016; p ublished online April 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Biotechnology; Biochemistry; Bioinformatics and Computational Biology; Molecular and Cell Biology; Plant Sciences and Forestry; Plant Physiology. 5053 words.

ABA is a phytohormone that is synthesized in response to abiotic stresses and other environmental changes, inducing various physiological responses. While ABA has been found in unicellular...

Absence of TLR4 Asp299Gly and Thr399Ile Polymorphisms in Chinese Han Population With Type 2 Diabetes

Peng-bin Lai, Lei Zhang, Sun-jie Yan and Li-yong Yang.

in Laboratory Medicine

September 2010; p ublished online October 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 1715 words.

Objective:

This study was performed to detect the association between the Asp299Gly and Thr399Ile polymorphisms of the TLR4 gene and type 2 diabetes in the...

Absolute Quantitation of Different Genotypes of Hepatitis C Virus RNA in Clinical Samples by a Modified Real-Time PCR Method

Karina del Carmen Trujillo-Murillo, Diana Cristina Pérez-Ibave, Clara Patricia Ríos-Ibarra, Eda Guadalupe Ramirez-Valles, Ana Rosa Rincón-Sánchez and Ana María Rivas-Estilla.

in Laboratory Medicine

June 2011; p ublished online October 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2425 words.

Background:

Our aim was to develop a quantitative real-time polymerase chain reaction (qPCR) assay for the quantitation of hepatitis C virus (HCV) RNA...

Accelerated acute severe antibody-mediated graft failure related to a Ross procedure 17 years earlier

Martin Andreas, Kathrin Freystaetter, Martin H Bernardi and Andreas Zuckermann.

in European Journal of Cardio-Thoracic Surgery

August 2018; p ublished online February 2018 .

Journal Article. Subjects: Molecular Biology and Genetics; Molecular and Cell Biology; Transplant Surgery; Cardiovascular Medicine. 749 words.

Abstract

A 31-year-old male patient underwent a heart transplantation due to dilated cardiomyopathy. He experienced accelerated acute antibody-mediated...

Acceleration of nucleation of prion protein during continuous ultrasonication

Kei-ichi Yamaguchi, Ryo P Honda, Abdelazim Elsayed Elhelaly and Kazuo Kuwata.

in The Journal of Biochemistry

June 2018; p ublished online February 2018 .

Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 6445 words.

Abstract

Although pulsatile irradiation of ultrasonication is frequently used for generating amyloid fibrils in vitro, the potential for inducing amyloid...

Accurate ab initio prediction of NMR chemical shifts of nucleic acids and nucleic acids/protein complexes

Andrea Victora, Heiko M. Möller and Thomas E. Exner.

in Nucleic Acids Research

December 2014; p ublished online November 2014 .

Journal Article. Subjects: Molecular and Cell Biology; Proteins; Molecular Biology and Genetics. 7813 words.

NMR chemical shift predictions based on empirical methods are nowadays indispensable tools during resonance assignment and 3D structure calculation of proteins. However, owing to the very...

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Activation of DC-SIGN Promoter and Common Signaling Pathways Between HIV-1 5′LTR and DC-SIGN

Changzhong Jin, Lijuan Wu, Jie Li, Linfang Cheng, Juan Wang and Nanping Wu.

in Laboratory Medicine

May 2013; p ublished online September 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2197 words.

Objective:

To explore whether expression of dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin (DC-SIGN) and reactivation of...

Activity-dependent functions of non-electrical glial cells

Daisuke Kato, Kei Eto, Junichi Nabekura and Hiroaki Wake.

in The Journal of Biochemistry

June 2018; p ublished online February 2018 .

Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 4884 words.

Abstract

Electrical activity is essential for brain function. However, neurons, the electrically active cells, are less numerous than the non-electrical glial...

Adaptation to the Local Environment by Modifications of the Photoperiod Response in Crops

Norihito Nakamichi.

in Plant and Cell Physiology

April 2015; p ublished online November 2014 .

Journal Article. Subjects: Molecular Biology and Genetics; Biotechnology; Biochemistry; Bioinformatics and Computational Biology; Molecular and Cell Biology; Plant Sciences and Forestry; Plant Physiology. 7373 words.

Flowering plants produce a meristem at the shoot tip where specialized tissue generates shoot apical meristems at the appropriate time to differentiate into reproductive structures,...

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Adenoviral gene transfer to the heart during cardiopulmonary bypass: effect of myocardial protection technique on transgene expression

J.M. Jones, K.H. Wilson, W.J. Koch and C.A. Milano.

in European Journal of Cardio-Thoracic Surgery

May 2002; p ublished online May 2002 .

Journal Article. Subjects: Cardiothoracic Surgery; Cardiovascular Medicine; Molecular and Cell Biology; Molecular Biology and Genetics. 3123 words.

Objective: Adenoviral gene transfer to the arrested heart during cardiopulmonary bypass (CPB) is a novel method of allowing prolonged vector contact with the myocardium. In...

Adiponectin suppression of late inflammatory mediator, HMGB1-induced cytokine expression in RAW264 macrophage cells

Mohamed Elfeky, Takeshi Yoneshiro, Yuko Okamatsu-Ogura and Kazuhiro Kimura.

in The Journal of Biochemistry

February 2018; p ublished online October 2017 .

Journal Article. Subjects: Cell Biology; Biotechnology; Biochemistry; Molecular and Cell Biology. 5939 words.

Abstract

High-mobility group protein B1 (HMGB1) is a late inflammatory mediator released from inflammatory cells when stimulated, resulting in exaggerating...

Advances in Molecular Cytogenetics to Study the Leukemia Genome

Jon C. Strefford and Christine J. Harrison.

in Laboratory Medicine

September 2007; p ublished online September 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 0 words.

The Advantages of Molecular Diagnostics in the Surveillance of Health Care-Associated Infections

Nicole L. Zitterkopf.

in Laboratory Medicine

October 2008; p ublished online September 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 0 words.

Health care-associated infections (HAIs) result in extensive morbidity and mortality. Studies indicate that placing a colonized or infected patient into contact isolation curtails the...

Age–gender considerations on survival in patients undergoing radial artery grafting

Andrea Ruzza.

in European Journal of Cardio-Thoracic Surgery

March 2015; p ublished online May 2014 .

Journal Article. Subjects: Molecular and Cell Biology; Molecular Biology and Genetics. 622 words.

Age-dependent trends in postoperative mortality and preoperative comorbidity in isolated coronary artery bypass surgery: a nationwide study

Kristinn Thorsteinsson, Kirsten Fonager, Charlotte Mérie, Gunnar Gislason, Lars Køber, Christian Torp-Pedersen, Rikke N. Mortensen and Jan J. Andreasen.

in European Journal of Cardio-Thoracic Surgery

February 2016; p ublished online February 2015 .

Journal Article. Subjects: Molecular Biology and Genetics; Molecular and Cell Biology. 4583 words.

OBJECTIVES

An increasing number of octogenarians are being subjected to coronary artery bypass grafting (CABG). The purpose of this study was to examine...

Air blockage at coronary anastomosis detected by intraoperative epicardial ultrasonography

Kenji Iino, Hiroki Kato, Yoshitaka Yamamoto and Hirofumi Takemura.

in European Journal of Cardio-Thoracic Surgery

July 2016; p ublished online January 2016 .

Journal Article. Subjects: Molecular Biology and Genetics; Molecular and Cell Biology. 290 words.