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A ‘tool box’ for deciphering neuronal circuits in the developing chick spinal cord

Yoav Hadas, Alex Etlin, Haya Falk, Oshri Avraham, Oren Kobiler, Amos Panet, Aharon Lev-Tov and Avihu Klar.

in Nucleic Acids Research

October 2014; p ublished online August 2014 .

Journal Article. Subjects: Molecular and Cell Biology; Research Methods in Life Sciences. 7453 words.

The genetic dissection of spinal circuits is an essential new means for understanding the neural basis of mammalian behavior. Molecular targeting of specific neuronal populations, a key...

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A 17-year, single-centre experience with the Ross procedure: fulfilling the promise of a durable option without anticoagulation?

Aleksandra Miskovic, Nadejda Monsefi, Afsaneh Karimian-Tabrizi, Andreas Zierer and Anton Moritz.

in European Journal of Cardio-Thoracic Surgery

February 2016; p ublished online March 2015 .

Journal Article. Subjects: Cardiovascular Medicine; Research Methods in Life Sciences. 4527 words.

OBJECTIVES

For adult patients <60 years with aortic valve disease, the Ross procedure is an attractive alternative to a prosthetic aortic valve. The Ross...

A 25-year study of chordal replacement with expanded polytetrafluoroethylene in mitral valve repair

Hiroki Hata, Tomoyuki Fujita, Yusuke Shimahara, Shunsuke Sato, Hatsue Ishibashi-Ueda and Junjiro Kobayashi.

in Interactive CardioVascular and Thoracic Surgery

April 2015; p ublished online December 2014 .

Journal Article. Subjects: Cardiovascular Medicine; Research Methods in Life Sciences. 4109 words.

OBJECTIVES

This study examines the outcome of mitral valve repair with chordal replacement using expanded polytetrafluoroethylene over the past 25 years.

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3.9 Å structure of the nucleosome core particle determined by phase-plate cryo-EM

Eugene Y.D. Chua, Vinod K. Vogirala, Oviya Inian, Andrew S.W. Wong, Lars Nordenskiöld, Juergen M. Plitzko, Radostin Danev and Sara Sandin.

in Nucleic Acids Research

September 2016; p ublished online August 2016 .

Journal Article. Subjects: Molecular and Cell Biology; Genetics and Genomics; Research Methods in Life Sciences; Proteins; Molecular Biology and Genetics. 3716 words.

The Volta phase plate is a recently developed electron cryo-microscopy (cryo-EM) device that enables contrast enhancement of biological samples. Here we have evaluated the potential of...

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About ILAR

in ILAR Journal

January 2013; p ublished online January 2013 .

Journal Article. Subjects: Research Methods in Life Sciences. 0 words.

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About ILAR

in ILAR Journal

January 2013; p ublished online January 2013 .

Journal Article. Subjects: Research Methods in Life Sciences. 0 words.

About ILAR

in ILAR Journal

January 2014; p ublished online January 2014 .

Journal Article. Subjects: Research Methods in Life Sciences. 0 words.

Go to »  abstract

About ILAR

in ILAR Journal

January 2014; p ublished online January 2014 .

Journal Article. Subjects: Research Methods in Life Sciences. 0 words.

About ILAR

in ILAR Journal

August 2015; p ublished online August 2015 .

Journal Article. Subjects: Research Methods in Life Sciences. 0 words.

About ILAR

in ILAR Journal

February 2016; p ublished online February 2016 .

Journal Article. Subjects: Research Methods in Life Sciences. 0 words.

About ILAR

in ILAR Journal

May 2015; p ublished online May 2015 .

Journal Article. Subjects: Research Methods in Life Sciences. 0 words.

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Absolute and relative quantification of RNA modifications via biosynthetic isotopomers

Stefanie Kellner, Antonia Ochel, Kathrin Thüring, Felix Spenkuch, Jennifer Neumann, Sunny Sharma, Karl-Dieter Entian, Dirk Schneider and Mark Helm.

in Nucleic Acids Research

October 2014; p ublished online August 2014 .

Journal Article. Subjects: Research Methods in Life Sciences. 7043 words.

In the resurging field of RNA modifications, quantification is a bottleneck blocking many exciting avenues. With currently over 150 known nucleoside alterations, detection and...

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Absolute quantitative measurement of transcriptional kinetic parameters in vivo

Sukanya Iyer, Bo Ryoung Park and Minsu Kim.

in Nucleic Acids Research

October 2016; p ublished online July 2016 .

Journal Article. Subjects: Research Methods in Life Sciences. 6534 words.

mRNA expression involves transcription initiation, elongation and degradation. In cells, these dynamic processes are highly regulated. However, experimental characterization of the dynamic...

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Accelerating Biomedical Discoveries through Rigor and Transparency

Judith A. Hewitt, Liliana L. Brown, Stephanie J. Murphy, Franziska Grieder and Shai D. Silberberg.

in ILAR Journal

July 2017; p ublished online May 2017 .

Journal Article. Subjects: Research Methods in Life Sciences. 9770 words.

Abstract

Difficulties in reproducing published research findings have garnered a lot of press in recent years. As a funder of biomedical research, the National...

Accurate detection for a wide range of mutation and editing sites of microRNAs from small RNA high-throughput sequencing profiles

Yun Zheng, Bo Ji, Renhua Song, Shengpeng Wang, Ting Li, Xiaotuo Zhang, Kun Chen, Tianqing Li and Jinyan Li.

in Nucleic Acids Research

August 2016; p ublished online May 2016 .

Journal Article. Subjects: Research Methods in Life Sciences. 9943 words.

Various types of mutation and editing (M/E) events in microRNAs (miRNAs) can change the stabilities of pre-miRNAs and/or complementarities between miRNAs and their targets. Small RNA (sRNA)...

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Accurate multiplexing and filtering for high-throughput amplicon-sequencing

Philippe Esling, Franck Lejzerowicz and Jan Pawlowski.

in Nucleic Acids Research

March 2015; p ublished online February 2015 .

Journal Article. Subjects: Genetics and Genomics; Bioinformatics and Computational Biology; Research Methods in Life Sciences. 8065 words.

Tagging amplicons with tag sequences appended to PCR primers allow the multiplexing of numerous samples for high-throughput sequencing (HTS). This approach is routinely used in HTS-based...

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Accurate quantification of DNA methylation using combined bisulfite restriction analysis coupled with the Agilent 2100 Bioanalyzer platform

Romulo Martin Brena, Herbert Auer, Karl Kornacker, Björn Hackanson, Aparna Raval, John C. Byrd and Christoph Plass.

in Nucleic Acids Research

February 2006; p ublished online February 2006 .

Journal Article. Subjects: Research Methods in Life Sciences. 5224 words.

DNA methylation is the best-studied epigenetic modification and describes the conversion of cytosine to 5-methylcytosine. The importance of this phenomenon is that aberrant promoter...

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Accurate transcriptome-wide prediction of microRNA targets and small interfering RNA off-targets with MIRZA-G

Rafal Gumienny and Mihaela Zavolan.

in Nucleic Acids Research

February 2015; p ublished online January 2015 .

Journal Article. Subjects: Genetics and Genomics; Research Methods in Life Sciences; Bioinformatics and Computational Biology. 8795 words.

Small interfering RNA (siRNA)-mediated knock-down is a widely used experimental approach to characterizing gene function. Although siRNAs are designed to guide the cleavage of perfectly...

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Achilles Tendon Injuries in Elite Athletes: Lessons in Pathophysiology from Their Equine Counterparts

Janet C. Patterson-Kane and Tina Rich.

in ILAR Journal

January 2014; p ublished online January 2014 .

Journal Article. Subjects: Research Methods in Life Sciences. 10007 words.

Superficial digital flexor tendon (SDFT) injury in equine athletes is one of the most well-accepted, scientifically supported companion animal models of human disease (i.e.,...

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Acinetobacter sp. ADP1: an ideal model organism for genetic analysis and genome engineering

David Metzgar, Jamie M. Bacher, Valérie Pezo, John Reader, Volker Döring, Paul Schimmel, Philippe Marlière and Valérie de Crécy-Lagard.

in Nucleic Acids Research

October 2004; p ublished online October 2004 .

Journal Article. Subjects: Research Methods in Life Sciences. 7329 words.

Acinetobacter sp. strain ADP1 is a naturally transformable gram-negative bacterium with simple culture requirements, a prototrophic metabolism and a compact genome of 3.7 Mb...