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Pathology x Preclinical Medicine x Haematology x Biological Sciences x clear all

The Association of NAD(P)H:quinine Oxidoreductase Gene Polymorphisms With Pediatric Acute Lymphoblastic Leukemia

Farhad Zaker, Akram Safaei, Nahid Nasiri, Maryam Abdollahzadeh and Vahid Pazhakh.

in Laboratory Medicine

November 2012; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 3188 words.

Objectives

Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. NAD(P)H:quinone oxidoreductase 1 (NQO1) is an enzyme that protects cells...

B Lymphoblastic Leukemia With a Novel t(11;15) (q23;q15) and Unique Burkittoid Morphologic and Immunophenotypic Findings in a 9-Year-Old Boy

Megan C. Smith, Megan K. Kressin, Eric Crawford, Xuan J. Wang and Annette S. Kim.

in Laboratory Medicine

November 2015; p ublished online November 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Haematology; Molecular and Cell Biology; Molecular Biology and Genetics. 2772 words.

B lymphoblastic leukemia is a B progenitor cell neoplasm with a range of immature immunophenotypes and several associated cytogenetic lesions. In contrast, Burkitt leukemia/lymphoma is a...

G6PD Deficiency and G6PD (Mediterranean and Silent) Polymorphisms in Egyptian Infants with Neonatal Hyperbilirubinemia

Zahraa M. Ezz El-Deen, Nouran F. Hussin, Tamer A. Abdel Hamid, Osman R. Abdel Migeed and Rania M. Samy.

in Laboratory Medicine

August 2013; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 3946 words.

Objective:

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common inherited cause of neonatal hemolytic anemia and jaundice. We investigated...

HIV-1 Viral Load Testing

Christine C. Ginocchio.

in Laboratory Medicine

March 2001; p ublished online September 2015 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Haematology; Chemistry; Molecular and Cell Biology; Molecular Biology and Genetics. 0 words.

Late Relapse of Acute Promyelocytic Leukemia: Literature Review and Results of Seven Years of Clinical and Laboratory Follow-Up of a Korean Patient

Min Jin Kim, Sun Young Cho, Hee Joo Lee, Jin-Tae Suh, Woo-In Lee, Juhie Lee, Sun Kyung Baek, Hwi-Joong Yoon and Tae Sung Park.

in Laboratory Medicine

August 2012; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2326 words.

Among patients with acute promyelocytic leukemia (APL), 10% to 30% experience relapse. Most relapses occur within 2 years; only a few, known as late relapses, occur 4 years after...

Molecular Diagnostic Testing in Hematologic Malignancies: A Brief Overview

Daniel E. Sabath.

in Laboratory Medicine

March 2004; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Chemistry; Molecular and Cell Biology; Molecular Biology and Genetics. 0 words.

Primary Lymphoma of Nasal Cavity and Paranasal Sinuses

Negar Azarpira, Mohammad J Ashraf, Ahmad Monabati, Alireza Makarempour, Bijan Khademi, Afsoon Hakimzadeh, Elham Abedi and Behnaz Valibeigi.

in Laboratory Medicine

November 2012; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2785 words.

Background

There are several reports of lymphomas arising in the nasal cavity, either T cell/NK cell or B cell type. We studied several cases of lymphoma...

Prothrombin G20210A Mutation in a 53-Year-Old Male Patient with Deep Vein Thrombosis

John Ecker and Carleen Van Siclen.

in Laboratory Medicine

February 2016; p ublished online January 2016 .

Journal Article. Subjects: Clinical Cytogenetics and Molecular Genetics; Haematology; Molecular and Cell Biology; Molecular Biology and Genetics. 1327 words.

Patient: A 53-year-old man, ethnicity unknown.

Chief Complaint: Leg swelling and pain.

History of Present Illness: The patient has a...

A Rare Finding in Acute Lymphocytic Leukemia: Philadelphia Chromosome

Alyssa Taylor and Carleen Van Siclen.

in Laboratory Medicine

May 2013; p ublished online October 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 938 words.

Patient:

48-year-old Caucasian male

Chief Complaint:

Gastrointestinal bleeding

Medical History:null...

Real-Time Polymerase Chain Reaction Testing for Quantitative Evaluation of hOCT1 and MDR1 Expression in Patients with Chronic Myeloid Leukemia Resistant to Imatinib

Saeed Solali, Saeed Kaviani, Ali Akbar Movassaghpour and Mohammad Reza Aliparasti.

in Laboratory Medicine

February 2013; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 3547 words.

Objective

To study quantitative expression of the genes MDR1 and hOCT1 in 30 patients with chronic myeloid leukemia (CML) and 27 healthy subjects.

null...

Reduction in Blood Culture Contamination Rates by Establishment of Policy for Central Intravenous Catheters

Dawn G. Ruge, Ramon L. Sandin, Sharon A. Siegelski, John N. Greene and Nancy Johnson.

in Laboratory Medicine

October 2002; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 0 words.

Study of Two Techniques for Heparin Therapy Monitoring With an Amidolytic Anti-Factor Xa Assay

Terry K. Rosborough and Patricia A. Wolfson.

in Laboratory Medicine

October 2002; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Chemistry; Molecular and Cell Biology; Molecular Biology and Genetics. 0 words.

The 3′End Prothrombin Gene Variants in Patients With Different Thrombotic Events

Valentina Djordjevic, Iva Pruner, Branko Tomic, Aleksandra Nestorovic, Maja Gvozdenov, Mirjana Kovac and Dragica Radojkovic.

in Laboratory Medicine

November 2014; p ublished online September 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2589 words.

Background:

Prothrombin (FII) A19911G and C20221T gene variants are associated with increased prothrombin levels and potentially represent thrombotic risk...

Three Different Co-existing α-Thalassemia Mutations and Sickle Cell Disease in a Pregnant Woman

Fakher Rahim, Fateme Hamid, Hamid Galedari, Gholamreza Khamisipour, Bijan Keikhaei, Kaveh Jaseb and Najmaldin Saki.

in Laboratory Medicine

February 2013; p ublished online October 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2185 words.

Thalassemia is the most frequent single-gene defect and overwhelmingly effects prenatal patients in Iran; the condition is caused by a diverse range of mutations. We discuss an extremely...

Thrombophilic Mutations in Iranian Patients With Thrombophilia

Poopak Behzad, Hamid Rezvani, Majid Farshdousti Hagh, Amal Saki, Parviz Fallah, Gelareh Khosravipour, Mohammad Ali Jahangirpour, Tolou Golkar, Shirin Sadat Bolouri Ebrahimi and Najmaldin Saki.

in Laboratory Medicine

February 2013; p ublished online October 2015 .

Journal Article. Subjects: Haematology; Clinical Cytogenetics and Molecular Genetics; Molecular and Cell Biology; Molecular Biology and Genetics. 2622 words.

Objectives

To investigate the frequency and type of Factor V Leiden (FVL), prothrombin, and methylenetetrahydrofolate reductase (MTHFR) mutations in ethnic...