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You are looking at 1-20 of 490 items for:

Overview x Clinical Pharmacology and Therapeutics x clear all

abciximab

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

The Fab fragments of a monoclonal antibody directed against the glycoprotein IIb/IIIa receptor on platelets that blocks platelet aggregation. Used as a short-term treatment to prevent...

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acamprosate calcium

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A drug used, in conjunction with counselling, for the maintenance of sobriety. Patients must already be abstinent at the beginning of treatment. It is administered orally; the most common...

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acarbose

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(ass-ar-bohz)

an oral hypoglycaemic drug that reduces the breakdown and absorption of carbohydrates in the intestine by blocking the action of an important enzyme (α-glucosidase)...

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ACE inhibitor

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(ayss)

angiotensin-converting enzyme inhibitor: any one of a group of drugs used in the treatment of raised blood pressure and heart failure. ACE inhibitors act by interfering with...

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acebutolol

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(ass-i-bew-toh-lol)

a beta blocker drug used to treat high blood pressure, angina pectoris, and irregular heart rhythms. It is administered by mouth. Trade name: Sectral.

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acetazolamide

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A carbonic anhydrase inhibitor that is used to treat glaucoma, epileptic seizures, benign intracranial hypertension, altitude sickness, cystinuria, and dural ectasia. TN Diamox.

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acetylcysteine

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(ass-i-tyl-sis-ti-een)

a drug that is administered as eye drops for the treatment of dry eyes, as in Sjögren's syndrome; as an intravenous infusion, it is used to prevent liver...

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aciclovir

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A nucleoside analogue (hydroxyethoxymethylguanine) with antiviral properties against both type 1 and 2 herpes virus and varicella-zoster virus. The drug is converted to the monophosphate by...

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acipimox

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A niacin derivative used to lower levels of cholesterol and other lipids in the blood by preventing the release of fatty acids from fatty tissue. TN Olbetam.

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acrivastine

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

An antihistamine drug that acts on the histamine H1 receptor, used to treat allergies and hay fever.

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activated charcoal

Overview page. Subjects: Clinical Pharmacology and Therapeutics — Public Health and Epidemiology.

A preparation of charcoal that can adsorb toxicants, e.g., narcotics, chlorine gas. It is used in water filtration devices to remove organic chemical contaminants from drinking water and as...

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adalimumab

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A human monoclonal antibody directed against tumour necrosis factor α and approved for treatment of inflammatory disease. Compare infliximab which is a humanized mouse monoclonal antibody...

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adefovir dipivoxil

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A drug used to treat chronic hepatitis B in patients who have not responded to or cannot tolerate interferon alfa or peginterferon alfa. It is administered by mouth; side-effects include...

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adjunct

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

(aj-unkt)

a subsidiary drug used in treating a disorder, which is administered in conjunction with, and provides additional benefits to, the main drug used in treatment.

—...

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alemtuzumab

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A humanized rat monoclonal antibody directed against CD52, used in the treatment of B-cell chronic lymphocytic leukaemia and as an immunosuppressive prior to transplant surgery.

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alendronic acid

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A bisphosphonate drug used to treat osteoporosis. The drug is adsorbed on to hydroxyapatite crystals in bone and inhibits osteoclast-mediated bone-resorption. TN Fosamax.

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alfentanil

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

n. an opioid analgesic drug used mainly for pain relief during surgery (see opiate). It is administered by intravenous injection or infusion, usually at induction of...

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alginic acid

Overview page. Subjects: Chemistry — Clinical Pharmacology and Therapeutics.

A hydrophilic polysaccharide (≈240 kDa) occurring in brown algae (brown seaweeds), especially the Californian giant kelp (Macrocystis pyrifera) and horsetail kelp (Laminaria digitata)....

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aliskiren

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

The first renin inhibitor developed; used to treat essential hypertension. Crystal structure analyses of renin–inhibitor complexes combined with computational methods were used in the...

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alkylating drug

Overview page. Subjects: Clinical Pharmacology and Therapeutics.

A cytotoxic drug that damages DNA: the addition of alkyl groups to guanine can lead to fragmentation during frustrated repair; nucleotides may be cross-bridged, blocking strand separation;...

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