Book

The Hippocampus Book

Edited by Per Andersen, Richard Morris, David Amaral, Tim Bliss [[missing key: and]] John O'Keefe

Published in print December 2006 | ISBN: 9780195100273
Published online May 2009 | e-ISBN: 9780199864133 | DOI: https://dx.doi.org/10.1093/acprof:oso/9780195100273.001.0001

Series: Oxford Neuroscience Series

The Hippocampus Book

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Computational Models of the Spatial and Mnemonic Functions of the Hippocampus

Burgess Neil.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 27971 words.

The use of computational models has been invaluable for exploring the link between neurons and behavior, enabling hypothetical mechanisms to be defined precisely and examined...

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Functional Role of the Human Hippocampus

Stark Craig.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 26554 words.

This chapter examines data from human amnesic patients, data from electrophysiological recordings in humans, and data from functional neuroimaging studies to address the question: What does...

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The Hippocampal Formation

Andersen Per, Morris Richard, Amaral David, Bliss Tim and O’Keefe John.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 4684 words.

This chapter begins with a brief discussion of the reasons behind the interest of scientists in the hippocampus. It then considers the importance of studying the hippocampus on its own,...

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Hippocampal Neuroanatomy

Amaral David and Lavenex Pierre.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 47383 words.

This chapter outlines the anatomy of the hippocampal formation, beginning with issues of nomenclature and definition. It compares and contrasts the picture of hippocampal anatomy obtained...

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Hippocampal Neurophysiology in the Behaving Animal

O’Keefe John.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 64174 words.

This chapter focuses on the neural correlates of hippocampal EEG and single-unit activity. It shows that EEG can be categorized into several frequency bands: theta, beta, gamma, and the...

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Hippocampus and Human Disease

Walker Matthew, Chan Dennis and Thom Maria.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 34425 words.

This chapter focuses on two disorders in which the role of the hippocampus has been extensively investigated: Alzheimer's disease and temporal lobe epilepsy. Although in Alzheimer's disease...

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Historical Perspective: Proposed Functions, Biological Characteristics, and Neurobiological Models of the Hippocampus

Andersen Per, Morris Richard, Amaral David, Bliss Tim and O’Keefe John.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 19704 words.

This chapter presents a historical discussion of the key discoveries and concepts of hippocampal neurobiology of the modern era up to about the 1970s. It is divided into two main sections....

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Local Circuits

Buhl Eberhard and Whittington Miles.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 17085 words.

This chapter demonstrates the basic principles involved in local circuits in general and reviews evidence for the organization of local circuits in the hippocampus. Local circuits in the...

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Molecular Mechanisms of Synaptic Function in the Hippocampus: Neurotransmitter Exocytosis and Glutamatergic, GABAergic, and Cholinergic Transmission

Osten Pavel, Wisden William and Sprengel Rolf.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 41636 words.

This chapter discusses the molecular biology of hippocampal cells with particular emphasis on synaptic function. It starts by describing the basis of all signal transmission processes, the...

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Morphological Development of the Hippocampus

Frotscher Michael and Seress László.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 12428 words.

This chapter considers how the hippocampus develops both from the perspective of overall organization and from that of individual cells. It begins by summarizing present knowledge on...

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Stress and the Hippocampus

Morris Richard.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 14235 words.

This chapter focuses on the role of the hippocampal formation and other “higher” structures, such as the amygdala and prefrontal cortex, in the negative feedback regulation of the...

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Structural and Functional Properties of Hippocampal Neurons

Spruston Nelson and McBain Chris.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 51374 words.

This chapter summarizes the wealth of structural, histological, and physiological information available for hippocampal neurons. Most of the data on this topic come from studies of the rat...

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Structural Plasticity

Gould Elizabeth.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 17883 words.

This chapter begins by discussing the types of structural plasticity in the hippocampal formation and then focuses on the evidence revealing that new neurons are formed in the dentate gyrus...

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Synaptic Function

Kullmann Dimitri.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 31642 words.

This chapter considers how the release of glutamate from presynaptic terminals in the hippocampus and its action on various glutamatergic receptors mediate excitatory synaptic transmission....

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Synaptic Plasticity in the Hippocampus

Bliss Tim, Collingridge Graham and Morris Richard.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 113189 words.

The chapter opens with a brief historical account of the first two decades of research into about long-term potentiation (LTP) and long-term depression (LTD). Section 10.2 discusses the...

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Theories of Hippocampal Function

Morris Richard.

in The Hippocampus Book

December 2006; p ublished online May 2009 .

Chapter. Subjects: Neuroscience. 111942 words.

This chapter considers a number of prominent theories of hippocampal function that have been developed from work on animals. Two theories have dominated research on hippocampal function...

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