Journal Article

Limits of agreement between measures obtained from standard laboratory and the point-of-care device Hemochron Signature Elite® during acute haemorrhage

T. Gauss, S. Hamada, I. Jurcisin, S. Dahmani, L. Boudaoud, J. Mantz and C. Paugam-Burtz

Edited by J. P. Thompson

in BJA: British Journal of Anaesthesia

Published on behalf of the British Journal of Anaesthesia

Volume 112, issue 3, pages 514-520
Published in print March 2014 | ISSN: 0007-0912
Published online December 2013 | e-ISSN: 1471-6771 | DOI: https://dx.doi.org/10.1093/bja/aet384
Limits of agreement between measures obtained from standard laboratory and the point-of-care device Hemochron Signature Elite® during acute haemorrhage

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Background

Rapid diagnosis of coagulopathy in the bleeding patient using point-of-care (POC) devices would be ideal. The Hemochron Signature Elite® (HC®) is a POC device that determines international normalized ratio (INR) and activated partial thromboplastin time (aPTT). The aim of the study was to evaluate the agreement for INR and aPTT between the HC® and standard laboratory values in acute haemorrhage.

Methods

This was a single-centre observational prospective study including patients with acute haemorrhage. Laboratory INR and aPTT were compared with simultaneous measurements performed with...

Keywords: blood coagulation disorders; haemorrhage; injuries; point-of-care systems; surgical blood loss

Journal Article.  4217 words.  Illustrated.

Subjects: Anaesthetics

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