Journal Article

Development of Three End-Capped Para-Benzoyl Calix[4,6, or 8]arene Bonded Stationary Phases for HPLC

Kai Hu, Ajuan Yu, Junqiang Zhang, Fuyong Wen, Song Liang, Xiaolan Zhao, Baoxian Ye, Yangjie Wu and Shusheng Zhang

in Journal of Chromatographic Science

Volume 50, issue 2, pages 123-130
Published in print February 2012 | ISSN: 0021-9665
Published online February 2012 | e-ISSN: 1945-239X | DOI:

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Three end-capped para-benzoyl calixarene bonded silica gel stationary phases are prepared and characterized by elemental analysis, infrared spectroscopy, and thermal analysis. The comparison and selectivity of these phases are investigated by using PAHs, disubstituted benezene, and naphthalene positional isomers as probes. Possible separation mechanism based on the different interactions between calixarenes and analytes are discussed. The results indicate that the separation for those analytes are influenced by the supramolecular interaction including π–π interaction, π-electron transfer interactions, space steric hindrance, and hydrogen bonding interaction on the calixarene columns. Importantly, the aromatic probes with polar groups such as –OH, –NO2, and –NH2 could regulate the selectivity of calixarene-bonded stationary phases.

Journal Article.  4611 words.  Illustrated.

Subjects: Chemistry