Journal Article

Correlation between biomarkers of human exposure to genotoxins with focus on carcinogen–DNA adducts

Erika Győrffy, Lívia Anna, Katalin Kovács, Péter Rudnai and Bernadette Schoket

in Mutagenesis

Published on behalf of United Kingdom Environmental Mutagen Society

Volume 23, issue 1, pages 1-18
Published in print January 2008 | ISSN: 0267-8357
Published online November 2007 | e-ISSN: 1464-3804 | DOI: https://dx.doi.org/10.1093/mutage/gem043
Correlation between biomarkers of human exposure to genotoxins with focus on carcinogen–DNA adducts

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  • Clinical Cytogenetics and Molecular Genetics
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Correlations among biomarkers, an important issue in biomarker research, provide enhanced insight and understanding of the complexity of molecular mechanisms initiated by environmental genotoxic agents in the human organism. Occupational and environmental exposures mostly represent mixtures of genotoxic agents, whereas the specificity of biomarker measurements varies widely. Here, we give an overview of the correlation studies with particular emphasis on DNA adduct biomarker analysis of exposure to polycyclic aromatic hydrocarbons (PAHs) and/or tobacco smoke. We have collected data on...

Journal Article.  11231 words.  Illustrated.

Subjects: Clinical Cytogenetics and Molecular Genetics ; Genetics and Genomics

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