In vitro synergistic activity against CCR5-tropic HIV-1 with combinations of potential candidate microbicide molecules HHA, KRV2110 and enfuvirtide (T20)
in Journal of Antimicrobial Chemotherapy
December 2009; p ublished online October 2009 .
Journal Article. Subjects: Medical Oncology; Critical Care. 1915 words.
Objectives
To block the different mechanisms of HIV mucosal transmission, it is likely that use of several microbicide molecules will lead to the best...
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Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytes
in Journal of Antimicrobial Chemotherapy
January 2010; p ublished online November 2009 .
Journal Article. Subjects: Medical Oncology; Critical Care. 5803 words.
Objectives
To analyse the oxidative and nitrosative stress response in Candida albicans generated by fluconazole at subinhibitory concentrations, and the...
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Adverse cutaneous reactions associated with the newest antiretroviral drugs in patients with human immunodeficiency virus infection
in Journal of Antimicrobial Chemotherapy
November 2008; p ublished online July 2008 .
Journal Article. Subjects: Medical Oncology; Critical Care. 7645 words.
HIV-infected patients have a higher risk of developing cutaneous reactions than the general population, which has a significant impact on patients’ current and future care options. The...
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Characterization of a major facilitator superfamily (MFS) tripartite efflux pump EmrCABsm from Stenotrophomonas maltophilia
in Journal of Antimicrobial Chemotherapy
November 2013; p ublished online June 2013 .
Journal Article. Subjects: Medical Oncology; Critical Care. 4806 words.
Objectives
To characterize the emrRCABsm operon of Stenotrophomonas maltophilia.
Methods
The presence of the emrRCA...
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An RND-type multidrug efflux pump SdeXY from Serratia marcescens
in Journal of Antimicrobial Chemotherapy
August 2003; p ublished online August 2003 .
Journal Article. Subjects: Medical Oncology; Critical Care. 2245 words.
Objectives: Serratia marcescens, an important cause of nosocomial infections, shows intrinsic resistance to a wide variety of antimicrobial agents (multidrug resistance)....
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Characterization of plasmids harbouring qnrS1, qnrB2 and qnrB19 genes in Salmonella
in Journal of Antimicrobial Chemotherapy
February 2009; p ublished online November 2008 .
Journal Article. Subjects: Medical Oncology; Critical Care. 4487 words.
Objectives
The aim of this study was to identify and characterize plasmids carrying qnrS1, qnrB2 and qnrB19 genes identified in Salmonella strains from The...
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A new member of the tripartite multidrug efflux pumps, MexVW–OprM, in Pseudomonas aeruginosa
in Journal of Antimicrobial Chemotherapy
October 2003; p ublished online October 2003 .
Journal Article. Subjects: Medical Oncology; Critical Care. 2559 words.
Objectives: Multidrug efflux pumps are thought to be involved in mediating multidrug resistance in Pseudomonas aeruginosa. Here we aim to characterize hitherto uncharacterized...
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The carbohydrate-binding plant lectins and the non-peptidic antibiotic pradimicin A target the glycans of the coronavirus envelope glycoproteins
in Journal of Antimicrobial Chemotherapy
October 2007; p ublished online August 2007 .
Journal Article. Subjects: Medical Oncology; Critical Care. 4976 words.
Objectives
Many enveloped viruses carry carbohydrate-containing proteins on their surface. These glycoproteins are key to the infection process as they are...
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IS26-mediated formation of a virulence and resistance plasmid in Salmonella Enteritidis
in Journal of Antimicrobial Chemotherapy
October 2017; p ublished online July 2017 .
Journal Article. Subjects: Medical Oncology; Critical Care. 2174 words.
Abstract
Objectives
To characterize a novel virulence–resistance plasmid pSE380T carried by a Salmonella enterica s...
A novel approach to the antimicrobial activity of maggot debridement therapy
in Journal of Antimicrobial Chemotherapy
August 2010; p ublished online June 2010 .
Journal Article. Subjects: Medical Oncology; Critical Care. 6733 words.
Objectives
Commercially produced sterile green bottle fly Lucilia sericata maggots are successfully employed by practitioners worldwide to clean a multitude...
The use of quaternary ammonium disinfectants selects for persisters at high frequency from some species of non-tuberculous mycobacteria and may be associated with outbreaks of soft tissue infections
in Journal of Antimicrobial Chemotherapy
December 2010; p ublished online October 2010 .
Journal Article. Subjects: Medical Oncology; Critical Care. 4414 words.
Background
Non-tuberculous mycobacteria (NTM) are increasingly important as opportunistic infections after major and minor surgical procedures, likely...
A single nucleotide in the promoter region modulates the expression of the β-lactamase OXA-61 in Campylobacter jejuni
in Journal of Antimicrobial Chemotherapy
May 2014; p ublished online January 2014 .
Journal Article. Subjects: Medical Oncology; Critical Care. 5125 words.
Objectives
Despite prevalent β-lactam resistance in Campylobacter jejuni, an important zoonotic enteric pathogen, the molecular basis of β-lactamase-mediated...
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Characterization of a novel Zn2+-dependent intrinsic imipenemase from Pseudomonas aeruginosa
in Journal of Antimicrobial Chemotherapy
November 2014; p ublished online July 2014 .
Journal Article. Subjects: Medical Oncology; Critical Care. 4080 words.
Objectives
Previous work showed that PA5542 inactivation increases Pseudomonas aeruginosa 59.20 susceptibility to carbapenems. The objective of the current...
In-vitro bactericidal efficacy of sub-MIC concentrations of liposome-encapsulated antibiotic against gram-negative and gram-positive bacteria.
in Journal of Antimicrobial Chemotherapy
January 1998; p ublished online January 1998 .
Journal Article. Subjects: Medical Oncology; Critical Care. 0 words.
It has been shown previously that tobramycin encapsulated in fluid liposomes (composed of dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylglycerol (DMPG)) eradicated mucoid...
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Multidrug resistance pump AcrAB-TolC is required for high-level, Tet(A)-mediated tetracycline resistance in Escherichia coli
in Journal of Antimicrobial Chemotherapy
July 2006; p ublished online May 2006 .
Journal Article. Subjects: Medical Oncology; Critical Care. 3399 words.
Objectives: Starting from the observation that Escherichia coli tolC mutations severely reduced the high-level resistance to tetracycline afforded by Tn10- and plasmid-encoded...
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Undecaprenyl pyrophosphate phosphatase confers low-level resistance to bacitracin in Enterococcus faecalis
in Journal of Antimicrobial Chemotherapy
July 2013; p ublished online March 2013 .
Journal Article. Subjects: Medical Oncology; Critical Care. 6121 words.
Objectives
Undecaprenyl pyrophosphate phosphatases (UppPs) have been implicated in bacitracin resistance in some bacterial genera and the aim of this study...
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Transcriptional analysis of and resistance level conferred by the aminoglycoside acetyltransferase gene aac(2′)-Id from Mycobacterium smegmatis
in Journal of Antimicrobial Chemotherapy
January 2008; p ublished online November 2007 .
Journal Article. Subjects: Medical Oncology; Critical Care. 3542 words.
Objectives
To analyse the correlation between the expression levels of the aac(2′)-Id gene from Mycobacterium smegmatis mc2155 and the resistance levels to...
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A non-infectious cell-based phenotypic assay for the assessment of HIV-1 susceptibility to protease inhibitors
in Journal of Antimicrobial Chemotherapy
January 2012; p ublished online October 2011 .
Journal Article. Subjects: Medical Oncology; Critical Care. 4156 words.
Objectives
HIV-1 genotyping is widely accepted as a diagnostic tool to optimize therapy changes in patients whose antiretroviral regimen is failing....
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Inhibition of infection and transmission of HIV-1 and lack of significant impact on the vaginal commensal lactobacilli by carbohydrate-binding agents
in Journal of Antimicrobial Chemotherapy
September 2013; p ublished online May 2013 .
Journal Article. Subjects: Medical Oncology; Critical Care. 7050 words.
Objectives
A selection of carbohydrate-binding agents (CBAs) with different glycan specificities were evaluated for their inhibitory effect against HIV...
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Expression of SCCmec cassette chromosome recombinases in methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis
in Journal of Antimicrobial Chemotherapy
April 2013; p ublished online December 2012 .
Journal Article. Subjects: Medical Oncology; Critical Care. 5038 words.
Objectives
Methicillin resistance in staphylococci is mediated by the mecA gene, which is carried on the staphylococcal cassette chromosome mec (SCCmec). SCCnull...
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